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Biomedical subjects

A Sismanis

Publications and source records attributed to A Sismanis.

66 records · Page 4Linked to original sources
PubMed1980

Facial paralysis of neoplastic origin: diagnosis and management.

The individual with a progressive (weeks to months) facial weakness should be considered to have a tumor involving the facial nerve until proved otherwise. All individuals experiencing a facial paralysis must undergo a thorough neurotologic evaluation to establish the etiology. Bell's palsy is a diagnosis by exclusion. While computerized axial tomography (CAT) scans, polytomography and arteriograms are extremely helpful, these studies very often fail to demonstrate intrinsic tumors involving the facial nerve. For this reason all individuals experiencing a progressive facial paralysis should have an exploration of their facial nerve from the internal auditory canal (IAC) through the stylomastoid foramen into the parotid gland. The purpose of this paper is to present a series of cases of facial paralysis having as their etiology intrinsic or extrinsic neoplasms. Clinical patterns are established, diagnostic protocols formulated and the results of surgical management reviewed.

Adolescent↗
PubMed1980

Carcinoma in situ of the ear canal.

A case of carcinoma in situ of the ear canal is presented. Review of the English literature failed to reveal a similar case. Wide local excision is the suggested mode of treatment.

Carcinoma in Situ↗
PubMed1980

Fine needle aspiration biopsy diagnosis of neck masses.

The cytologic findings in 107 aspiration smears obtained with the fine needle technique from head and neck masses were compared with the histologic findings in permanent sections. The overall concurrence rate between cytologic and histologic findings in benign and malignant tumors was 82.2 per cent. There was a 5.6 per cent incidence of false negative findings. There were no false positive results. Fine needle aspiration was found to be safe, complication free, and most helpful in planning treatment. We recommend the technique to others who deal with head and neck masses.

Biopsy, Needle↗
PubMed1979

Rare congenital syndrome associated with profound hearing loss.

In this communication, we describe the otologic and audiometric findings of a rare congenital syndrome associated with profound hearing loss. We offer a hypothesis of the possible inner ear pathologic condition. The major anomalies of this syndrome represent features of an ectodermal dysplasia syndrome.

Abnormalities, Multiple↗
PubMedDate not supplied

Diagnosis of salivary gland tumors by fine needle aspiration biopsy.

The cytologic findings of 51 smears obtained by fine needle aspiration biopsy from salivary gland masses were compared with the histologic findings of permanent sections. The overall concurrence rate between cytologic and histologic findings for being and malignant lesions was 91%. The diagnostic accuracy (exact histologic diagnosis) for the benign lesions was 87% and for the malignant tumors 60%. One case showed false-positive results and 1 case false-negative results. Fine needle aspiration biopsy has been found to be safe, free of complications, and helpful in the planning of treatment.

Adult↗
PubMedDate not supplied

Medical management of Menière's disease.

The medical management of Menière's disease appears to be a misunderstood and controversial subject. There are those physicians who state that all cases can be controlled by medical means and that surgery is never indicated. Another group of investigators now emphasizes early surgical intervention without a medical trial. These conflicting views have led the authors to review all of their cases of Meniére's disease (almost 1,000) in relation to medical management. The medical regime and its rationale are presented in detail. The results of this therapy are discussed in the context of control of vertigo, relief of tinnitus and pressure, and the stabilization of hearing.

Adult↗
PubMedDate not supplied

Simultaneous carcinomas of the esophagus and upper aerodigestive tract.

A review of 150 consecutive head and neck cancer patients over a 22-month period revealed a multiple primary cancer rate of 19%, 9% in the head and neck region. Nine patients (6%) had simultaneous esophageal and head and neck cancers. Complete systematic esophagoscopic examinations, in addition to barium swallow radiographic studies, are recommended for all patients with head and neck cancers.

Adult↗
PubMedDate not supplied

Diagnostic value of fine needle aspiration biopsy in neoplasms of the head and neck.

In this paper, the cytologic findings of 90 aspirates obtained by the fine needle aspiration technique from head and neck masses are compared with the histology of the permanent section. The overall concurrence rate between cytologic and histologic findings for benign and malignant tumors is 80%. There is a 6.6% false negative rate. There are no false positive results. Fine needle aspiration biopsy is found to be safe, complication free, and most helpful in treatment planning.

Biopsy, Needle↗
PubMedDate not supplied

Myelin and axon degeneration following direct current peripheral nerve stimulation: a prospective controlled experimental study.

A previous study by the authors compared pathologic changes in the mouse sciatic nerve following prolonged continuous stimulation with either pulsed or direct current. The pulsed current stimulator was found as equally effective yet far safer than the direct current (DC) stimulator. In an attempt to reproduce more accurately the clinical setting, the Ear, Nose, and Throat Device Classification Panel of the Food and Drug Administration requested a prospective, controlled study of repeated DC stimulation at one or more sites along a peripheral motor nerve. Again, repetitive DC stimulation both at one site and at multiple sites of the same nerve produced significant myelin and axon degeneration. The authors conclude that even routine use of the DC stimulator carries with it the potential for permanent nerve damage and muscle paralysis.

Animals↗
PubMedDate not supplied

Cerebrospinal fluid "leaks" and meningitis following acoustic tumor surgery.

We reviewed 271 intracanalicular and cerebellopontine angle lesions removed over the past ten years, 237 by the translabyrinthine or combined approach which created a mastoid defect. The patients were divided into three groups with the following results: (1) obliteration of the mastoid defect combined with older wound closure techniques in the first 188 patients produced CSF leakage in 25% and meningitis in 16% of cases; (2) not obliterating the defect intentionaly in 16 patients produced CSF leakage in 50% and meningitis in 25% of cases; (3) obliteration of the defect combined with newer packing and closure techniques in the last 33 patients produced CSF leakage and meningitis in only 6% of cases. Four problem areas were identified: the eustachian tube, middle ear, mastoid defect, and postauricular wound. Of these, obliteration of the mastoid defect was most important in minimizing postoperative CSF wound leakage, CSF rhinorrhea, and meningitis.

Aged↗