An evaluation survey (1991-92) on utilization and awareness of ICDS services among pregnant and lactating women revealed that in subcentre areas beneficiaries were less aware of location and staff of anganwadi centre (AWC) and that they visited AWC less often as compared to their counterparts in non-subcentre areas. More beneficiaries in subcentre area said that immunization services provided by AWC were inadequate as compared to the responses in non-subcentre area. A different role for AWC & its staff in subcentre headquarter villages is recommended.

Breast Feeding↗

PubMedDate not supplied

Specific IgE to castor bean (Ricinus communis) pollen in the sera of clinically sensitive patients to seeds.

Human sensitization to castor bean seeds in occupational workers and people living close to oil processing factories has been acknowledged for a long time. In view of the cross-reactivity among different plant parts of the same species, we studies crossreactivity between seeds of castor bean and its pollen at the molecular level. Sera from 26 seed-positive atopics, when analyzed for ELISA against seed and pollen extracts of castor bean, showed binding with both seed and pollen extracts, but binding was stronger with seed extracts as compared to pollen. ELISA inhibition revealed partial similarity as pollen extract could not achieve 90% inhibition even at 100 micrograms/ml, and remained the same after protein concentrations of 40 micrograms/ml. Antigenic extracts of seeds and pollen separated into 12 and 20 fractions on SDS-PAGE, respectively. The 26 sera studied for specific IgE binding to different fractions of seed and pollen extracts showed IgE binding in 17 and 16 cases respectively, but with weak binding to pollen fractions. The crossreactivity was confirmed with pooled sera by blot inhibition. Seed antigen completely inhibited the sera for specific IgE at 10 mg/ml protein while pollen antigen showed only partial inhibition. Crossreactivity and presence of common epitopes between seed and pollen extracts are confirmed.

Allergens↗

PubMedDate not supplied

Xanthogranulomatous pyelonephritis.

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Adult↗

PubMedDate not supplied

Perinatal influence of Chlorella vulgaris (E-25) on hepatic drug metabolizing enzymes and lipid peroxidation.

This study evaluates the potential for the perinatal transfer of active constituents and/or metabolites of Chlorella vulgaris (E-25) via modulating the hepatic level of drug metabolizing enzymes and lipid peroxidation. E-25 (100, 300 or 500 mg/kg b.w./day) induced a significant increase in the hepatic levels of glutathione S-transferase (GST) and sulfhydryl (-SH) in fetal and neonatal systems after 14 days treatment to gestating or lactating mice. E-25 (500 mg/kg b.w./day)-modulated inhibition of cytochrome b5 (Cyt. b5), cytochrome P-450 (Cyt. P-450) and malondialdehyde (MDA) level was observed in the fetal and neonatal hepatic tissue following the transplacental or translactational exposure. The observed modulation in the levels of hepatic drug metabolizing enzymes and lipid peroxidation suggest the chemopreventive potential of E-25 via perinatal passage of active constituents and/or metabolites.

Animals↗