Functional phenomenon: historical concept, contemporary defense.
Explore the source record for details and available documents.
Adult↗
Biomedical subjects
A Silber
Publications and source records attributed to A Silber.
A patient's gift: its meaning and function.
Explore the source record for details and available documents.
Humans↗
Changes in biophysical parameters and in phospholipid composition associated with resistance to doxorubicin.
Friend leukemia cells (FLC) resistant to different concentrations of doxorubicin were used to investigate the biochemical and biophysical changes associated with resistance. We have found that fluorescence polarization of 1,6-diphenyl-1,3,5-hexatriene analyzed on single cell level increased in resistant as compared to sensitive FLC. Furthermore, phospholipid analysis of sensitive and doxorubicin-resistant cells revealed changes in ratios of phosphatidyl-choline to phosphatidyl-ethanolamine and phosphatidyl-choline to sphingomyelin. These results correlate with decreased electrophoretic mobility in resistant cells. Our results indicate that changes in cell structure occur with the level of resistance to doxorubicin. These changes are probably the consequence rather than the cause of resistance.
Cells, Cultured↗
The importance of "real" trauma on phobic symptom formation.
Explore the source record for details and available documents.
Agoraphobia↗