Diagnosis and treatment of acute abdominal conditions with special reference to roentgenographic findings.
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Biomedical subjects
Publications and source records attributed to A Shirota.
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Primary rhabdomyosarcoma of the alimentary tract is extremely rare, only 11 cases have been reported in the literature. Long-term survival in adults may be possible if the tumor is detected at an early stage even though it is asymptomatic. This highly malignant tumor can be treated by surgical excision, chemotherapy, and irradiation. A 12th case--of stage 1, pararectal, rhabdomyosarcoma--is reported.
A 27-year-old man was found to have a mediastinal tumour and the histological diagnosis was immature teratoma. Remission was achieved by chemotherapy and total resection. However, he developed anaemia and leukoerythroblastosis after 2 years of remission, and was referred to our hospital. Rhabdomyosarcoma cells were detected in the bone marrow and pleural effusion. Moreover, karyotype analysis of peripheral blood and bone marrow cells revealed mosaic-type Klinefelter syndrome. We diagnosed the case as transformation of teratoma into rhabdomyosarcoma in Klinefelter syndrome. Although intensive chemotherapy was performed, the patient died with meningeal infiltration.