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Biomedical subjects

A Shimazu

Publications and source records attributed to A Shimazu.

At least 109 records · Page 6Linked to original sources

A new method of electrodiagnosis during operations on the brachial plexus and peripheral nerve injuries. The value of motor nerve action potentials evoked by trans-skull motor area stimulation.

A method is described which records efferent motor nerve action potentials (MNAPs), evoked by trans-skull motor area stimulation, directly from a nerve root or peripheral nerve fibres during operation. The records of MNAPs from the root show whether function of the anterior root is intact and its continuity retained. When recorded from the proximal stump of a divided nerve at the wrist the motor funiculus can be identified, enabling funicular nerve suture to be carried out more easily.

Action Potentials↗

Lactoquinomycin, a novel anticancer antibiotic. I. Taxonomy, isolation and biological activity.

Lactoquinomycin, a novel basic antibiotic, was isolated from the culture broth of a soil streptomyces by repeated solvent extraction and adsorption column chromatography. Morphological, cultural and physiological studies revealed that the organism belongs to the species Streptomyces tanashiensis. The antibiotic was active against bacteria, particularly Gram-positive organisms, and neoplastic cells in vitro. Antibiotic-resistant cell sublines of L5178Y lymphoblastoma were more significantly inhibited by lactoquinomycin than the parental cell line. Lactoquinomycin was effective against Ehrlich carcinoma in mice.

Animals↗

A new imaging agent for medullary carcinoma of the thyroid.

Thyroid scintigraphy, using 99mTc(V) dimercaptosuccinic acid, was performed in four patients with pathologically confirmed medullary thyroid carcinoma and elevated serum calcitonin values. Significant uptake of the tracer was found in the clinically palpable cervical tumor masses, metastatic sites, and residual tumor. This finding, probably specific for medullary thyroid carcinoma, could be of great use in the diagnosis and the surgical follow-up.

Adenocarcinoma↗