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Biomedical subjects

A Shimada

Publications and source records attributed to A Shimada.

At least 325 records · Page 18Linked to original sources
PubMed1979

Fecal bile acids in two Japanese populations with different colon cancer risks.

Some workers have associated fecal bile acids with colon cancer frequency. They suggest that the risk for colon cancer increases with a rise in the level of total and degraded fecal bile acids. The Japanese in Hawaii, who are at high risk for this cancer, had higher concentrations of deoxycholic acid (a degraded bile acid) in their fecal specimens than did the people in Akita, Japan, who are at low risk. However, the findings for the other bile acids were unremarkable or inconsistent. These data were suggestive, but not strongly supportive, of a relationship between fecal bile acid patterns and colon cancer risk.

Adult↗
PubMed1977

Bowel transit-time and stool weight in populations with different colon-cancer risks.

It has been suggested that the risk of cancer, polyposis, and diverticulosis of the large bowel increases with bowel transit-time. Hence, Japanese inhabitants of Hawaii, in whom the risk of these diseases is high, would be expected to have longer transit-times than Japanese in Japan, in whom such risks are low. However, bowel transit-times were similar in Japanese groups. Stools from the Hawaii Japanese did weight significantly less than the specimens from Japan, and this factor may be indirectly related to the risk of colorectal cancer, polyposis, or diverticulosis in the Japanese.

Aged↗
PubMed1975

[Limiting amino acids of chickpeas (Cicer arietinum) for chickens and pigs].

Three experiments, two with broilers and one with pig, were conducted to determine the limiting amino acids of chickpea (Cicer arietinum). In the first 15% protein diets based on autoclaved chickpea were supplemented with methionine (0.20%), either alone or combined with threonine (0.025%) with no significant effect on growth or feed convertion of chicks; however, the addition of methionine tended to improve both parameters in relation to the unsupplemented diet. In the second experiment methionine (0.20%) and/or tryptophan (0.03%) were added to 15% protein diets based on either raw or autoclaved chickpeas. Cooking improved growth and feed efficiency in relation to the raw controls (P less than .05); methionine supplementation was beneficial for both raw and autoclaved diets (P less than .01); the addition of tryptophan was favourable only for the cooked chickpeas. A third experiment was conducted with weanling pigs to study the effect of methionine supplementation to sorghum-chickpea diets with 14 and 12% protein. In both cases, the addition of the sulphur amino acid improved growth and efficiency to the levels obtained with a 15.34% protein sorghum-soybean meal control.

Amino Acids↗
PubMed1975

The maturation of reticulocytes. I. Following introduction of reticulocytes into polycythemic and normocythemic animals.

Investigations were conducted on the life-span of "stress" reticulocytes and the fate of the early denucleated large-sized reticulocytes in circulating blood. Reticulocyte disappearance was examined after reticulocyte introduction into the vein and into the peritoneal cavity of polycythemic and normocythemic animals. The results indicated that these introduced reticulocytes matured to red cells by about 36 hours after injection under both the polycythemic and normocytehmic conditions. The large-sized reticulocytes disappeared by about 4 to 12 hours after introduction. The maturation of reticulocytes was largely arrested when the cells were introduced into the peritoneal cavity.

Animals↗
PubMed1975

The maturation of reticulocytes. II. Life-span of red cells originating from stress reticulocytes.

Life-spans of macroreticuloytes and macrocytic red cells were studied. Rabbits were made anemic by injecting phenylhydrazine. Peripheral blood rich in reticulocytes was drawn, labeled with 3H-amino acids, and injected back into the anemic animal. Autoradiographic observation on circulating red cells revealed that macroreticulocytes matured at nearly the same time as normal-sized reticulocytes but that the macrocytic red cells had a short life-span compared to normal-sized red cells.

Anemia, Macrocytic↗