Search PubMed⌕ Search

Biomedical subjects

A Shaw

Publications and source records attributed to A Shaw.

At least 361 records · Page 20Linked to original sources
PubMedDate not supplied

Oral health in elderly patients.

A study of the oral health of elderly institutionalised patients and their oral care has revealed significant deficiencies, illustrating the need for a multi-disciplinary approach to oral health care centred on the development of mouth care regimens for nursing staff.

Aged↗
PubMedDate not supplied

Efficacy of a nelfinavir- and nevirapine-containing salvage regimen.

PURPOSE: In this study, our purpose was to assess the efficacy of nelfinavir- and nevirapine-containing salvage regimens in nonnucleoside reverse transcriptase inhibitor (NNRTI)-naive patients virologically failing a protease inhibitor (PI)-based combination. METHOD: A retrospective case note review of all patients virologically failing their PI-based combination who were switched to a regimen containing both nelfinavir (1 g t.d.s.) and nevirapine (200 mg b.d.). CD4 cell counts and viral loads were monitored. Genotypic analysis was performed using RT-PCR sequencing. RESULTS: Nineteen patients commenced a salvage regimen containing nelfinavir and nevirapine. Five patients also changed at least one nucleoside reverse transcriptase inhibitor (NRTI), although in one case this represented recycling. Thirty-eight percent (6/16) of patients achieved a viral load below the level of detection (BLD; <200 copies/mL; complete responders [CR]), 3 achieved <20 copies/mL. Five patients achieved > or =1 log drop (partial responders [PR]) that was not sustained over follow-up, and five failed to respond to therapy (nonresponders [NR]). CRs tended to have wild-type NNRTI and PI sequences relative to PRs and NRs. CONCLUSION: In heavily pretreated patients, a nelfinavir-and nevirapine-containing salvage regimen resulted in a virological response in 38% of patients that was sustained in 31% over 63 weeks.

Adult↗
PubMedDate not supplied

Tourniquets for surgery: safety aspects.

There are a variety of different types of pneumatic tourniquets in constant use within the UK Health Service. These range from simple manually operated units to more complex gas-powered devices. Fatalities have occurred following the failure of pneumatic tourniquets during surgery when the local anaesthetic agent administered to the patient entered the circulation. Investigation has revealed that certain tourniquet systems have design defects, for example deterioration of rubber tubing, inadequate securing of pressure tubing, excessive wear in a pressure regulator. With any tourniquet system, routine maintenance coupled with regular user checks are essential to ensure reliability.

Equipment Safety↗
PubMedDate not supplied

A syringe pump tester.

The equipment described allows the accuracy of a syringe pump to be tested quickly and conveniently. A digital micrometer assembly clips in place of the disposable syringe and transmits readings to a separate unit which displays flow rates in ml/h. Initial readings of pump output are given in 30 s, with readings to a higher accuracy within 4 min.

Calibration↗
PubMedDate not supplied

Evaluation of Makita electric drills for orthopaedic surgery.

The problems associated with the use of air drills in orthopaedic surgery are briefly reviewed. Battery-powered electric drills offer an alternative but they can introduce a different set of problems. We have investigated procedures for using a Makita, non-medical battery-powered drill in orthopaedic surgery and can conclude that, within certain limits, this drill is an alternative to an air drill with the advantage of absence of air hoses and the potential for cost-saving.

Ethylene Oxide↗
PubMedDate not supplied

BSI certification.

Explore the source record for details and available documents.

Equipment and Supplies↗
PubMedDate not supplied

Infection control when servicing medical and laboratory equipment.

The risks of infection in servicing medical and hospital laboratory equipment are reviewed. Recommended procedures and precautions for dealing with these risks are detailed. These are based upon the practice adopted in the authors' own department. A 'permit to work' scheme is not felt to be universally applicable and the guiding criteria to judge any applied procedure are set down.

Acquired Immunodeficiency Syndrome↗