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Biomedical subjects

A Shaw

Publications and source records attributed to A Shaw.

At least 271 records · Page 15Linked to original sources

Intussusception.

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Biopsy↗

Subcutaneous reduction clitoroplasty.

Congenital clitoral hypertrophy should be corrected in infancy. Most surgeons perform a total clitroectomy or one of several kinds of clitoral recession procedures. There are some reasons for dissatisfaction with both of these alternatives. An operation in which the corpora cavernosum are resected subcutaneously and the glans sutured to the pubis preserves blood supply and sensation and results in a perineal appearance close to normal. The author has performed this operation infive cases of clitoral hypertrophy associated with adrenogenital syndrome and suggests a wider trial of procedure.

Adrenal Hyperplasia, Congenital↗

Two-dimensional echocardiography with a wide angle (60 degrees) sector scanner.

A wide angle (60 degrees) sector scanner producing a real-time two-dimensional echocardiogram has been used to examine healthy infants, children, and adults. Its method of use is described and findings from longitudinal and transverse scans are presented. The points of difference between the various types of electronic and mechanical two-dimensional scanning systems are discussed. This equipment minimises problems of chest contact and rib and lung interference and, by providing echocardiograms of high line density from a wide angle, is a suitable real-time two-dimensional scanning system for examining patients of all ages.

Adult↗

Ethical issues in pediatric surgery: a national survey of pediatricians and pediatric surgeons.

The findings reported in this article are based on a nationwide survey of the attitudes and practices of pediatric surgeons and pediatricians with respect to some of the difficult ethical choices confronting them in medical practice. Four hundred fifty-seven physicians completed a questionnaire in the spring of 1975 in which they reacted to a wide range of issues that have been of increasing concern to the public, as well as to the medical profession. The survey attempts to identify some areas of physician consensus as well as some of the factors, personal and professional, influencing physicians' attitudes. The survey and its statistical analysis are intended to provide current sociological data and are not intended by the authors as an endorsement of any particular point of view or course of action.

Adult↗

Requirement for accessory cells in the antibody response to T cell-independent antigens in vitro.

The antibody responses of mouse spleen cells in vitro to three thymus-independent (TI) antigens namely, polymeric flagellin (POL) of Salmonella adelaide, DNP-Ficoll and "soluble" sheep erythrocyte (SRBC) antigen, were found to be dependent on adherent accessory cells (A cells) but to a lesser degree than the response to intact SRBC. Evidence for this comes from selective depletion of A cells from spleen cells and reconstitution with A cell-rich populations. Thus, depletion of A cells by adherence on glass resulted in abolition of the response to SRBC leaving the response to POL intact. More thorough removal of A cells by treatment with carbonyl iron powder was required for appreciable reduction of the responses to POL, DNP-Ficoll and "soluble" SRBC. This reduction in responsiveness was not due to poor cell survival after A cell depletion or to the loss of immunocompetent cells since 1) the recoveries of viable cells in all cultures were similar; 2) the contents of theta- and Ig-bearing cells and tritium-labeled POL-binding cells were unaltered after carbonyl iron treatment, and 3) responsiveness was fully restored by the addition of irradiated and anti-theta-treated A cells from the peritoneal cavity or the spleen. Hence, the hitherto A cell independence of TI antigens on which some theories of B cell activation are based is a result of inadequate depletion procedures, and the minimal model for B cell activation must take into account two cell types: B cells and A cells.

Animals↗

A real time 2-dimensional ultrasonic scanner for clinical use.

The technical details of a real time 2-dimensional ultrasonic scanning system are described, with particular regard to the improved clinical performance over other 2-dimensional scanners. Our instrument is capable of being used with existing ultrasonic equipment extending certain standard ultrasonic machines for use as real time 2-dimensional scanners conveniently and at little cost. Initial results are given and future technical developments are discussed.

Echocardiography↗