Biomedical subjects
A Senapati
Publications and source records attributed to A Senapati.
Is tissue copper deficiency associated with aortic aneurysms?
It has been suggested that patients with abdominal aortic aneurysms are deficient in tissue copper. Levels of copper and zinc in liver and aortic wall were therefore measured in 11 patients with aortic aneurysms and 11 fresh cadavers with normal aortas. The concentrations of copper were similar in both groups. Zinc concentration was higher in the normal aortic wall, probably because of the greater thickness of the media in the normal aorta. We found no evidence that aortic aneurysms are associated with reduced tissue copper concentrations.
Zinc deficiency and the prolonged accumulation of zinc in wounds.
Zinc is required for protein synthesis and therefore for wound healing. Zinc levels were 50 per cent higher in muscle and skin from abdominal wounds of rats during the maturation phase of wound healing, but mild deficiency greatly reduced this accumulation. The results suggest that zinc takes part in the late stages of wound healing when protein is laid down, and that such extra local demands expose otherwise marginal zinc deficiency.
A comparison of preoperative long saphenous phlebography with operative dissection in assessing the suitability of long saphenous vein for use as a bypass graft.
A technique for assessing the anatomy and luminal diameter of the long saphenous vein by direct injection phlebography in patients being considered for reversed femoropopliteal vein bypass surgery is described. In 25 consecutive patients, 20 single veins, four double veins and one network of veins were all correctly delineated by this technique and subsequently confirmed at operation. Five saphenous veins could not be demonstrated above the knee but at operation one vein was found to be present and double from knee to groin. The minimum mean luminal diameter of the saphenous vein estimated from the X-ray after correction for magnification was 3.5 mm +/- 1.12 which was significantly less than the mean external diameter found at operation, 4.6 mm +/- 1.33 (P less than 0.001). The vein diameter found at operation invariably proved to be larger than the luminal diameter estimated from the X-ray. This allows a confident preoperative assumption of the minimum diameter that will be obtained after dissection and distension of the vein.
Accessory cystic duct--an operative hazard.
Two patients with duplicated cystic ducts are reported. This is a rare and poorly reported anomaly. The hazards of misdiagnosis are discussed.
Spontaneous dehiscence of an incisional hernia.
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Gluteal necrosis and paraplegia following postoperative bilateral internal iliac artery occlusion.
Complications associated with occlusion of the internal iliac arteries are seen less commonly than those following occlusion of the external iliac arteries, because the pelvis has a good collateral circulation. This paper describes a case of severe gluteal necrosis, paraplegia and acute renal failure following an aorto-bifemoral bypass, which we believe was caused by bilateral iliac artery and pelvic collateral circulation occlusion.
Differentiation of ruptured aortic aneurysm from acute expansion by computerised tomography.
CT scans were obtained in five patients who presented with abdominal pain and were found to have an abdominal aortic aneurysm without evidence of hypovolaemia. A periaortic haematoma and evidence of a rupture was found on scanning in three of the patients and confirmed at immediate operation. A retrospective diagnosis of rapidly expanding (acute) aneurysm was made in the other two patients in whom no other pathology was found at early elective operation. CT scanning is useful in differentiating small well-controlled ruptures from rapidly expanding aneurysms.