Biomedical subjects
Publications and source records attributed to A Scurelli.
The authors present a case of Caroli's disease complicated with multiple lithiasis and cholangiocarcinoma. They analyse the etiopathogenesis and the anatomopathologic features of this uncommon disease and express some diagnostic and therapeutic considerations.
The authors report a case of Zenker's giant hypopharyngeal diverticulum in an elderly patient who underwent surgery due to the severity of symptoms. This diverticulum, which is both juxtasphincteric and epiphrenal, has a pulsion pathogenesis: the presence of a hernia on the esophageal side (jato?), with which Zenker's diverticulum is frequently associated and which is often followed by reflux esophagitis, is enough to cause motor asynchronism of the crico-pharyngeal muscle which, in the presence of hypertonic conditions during deglutition, leads to the formation of a high-pressure pouch which is then responsible for the formation of the diverticulum itself. It is therefore important to check whether an associated esophageal pathology exists once Zenker's diverticulum has been diagnosed: X-ray examinations of the upper digestive tract are undoubtedly capable of identifying the presence of the diverticulum as well as other pathological associations. In the present case it was not possible to perform a sufficiently exhaustive X-ray examination in order to exclude associated esophageal pathologies. Endoscopy may be superfluous and contraindicated in cases of large diverticular pouches. Symptoms vary depending on the size of the diverticulum. A feeling of dysphagia may precede the appearance of the diverticulum, even by several years, before the onset of symptoms related to the ingestion of food: initially the patient may experience the sensation of a foreign body while eating due to the accumulation of ingested food in the diverticulum; this is followed by halitosis, sialorrhea, noisy deglutition, regurgitation of undigested food especially during sleep, and frequently bronchopulmonary symptoms "ab ingestis".(ABSTRACT TRUNCATED AT 250 WORDS)
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
A case of diffuse rectocolonic melanosis in association with severely dysplasic recurring multiple adenomas is reported. The rarity of the condition gives rise to remarks based on a review of recent literature on the subject.
Explore the source record for details and available documents.
A case of enterogenous cyst of the mesosigmoid, exceptional for its abrupt onset and rapid course is reported in a woman of 65. Preoperative diagnosis at this age in practically impossible, but the operation and refined histological development is always unpredictable and never negligible. Although there was no presence of aetiopathogenetic originality, presentation and study of the clinical case had the purpose of informing the surgeon that surprises must always be notified, just as must any exceptionally rare anatomopathological finding.
Reference is made to the APUD system and the APUDoma concept, and stress is laid on certain correlations noted between the histochemical features, endocrine activity, and topographical distribution of digestive tract carcinoids. Lastly, a description is given of a advanced stage, when metastases were already present on the soft parts of the left thigh, and in both kidneys, the liver, and the left lung. The occasion is taken to put forward some observations of a clinical, prognostic, and diagnostic order.