[Harmonic analysis of atrial depolarization in high-resolution electrocardiography].
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Biomedical subjects
Publications and source records attributed to A Sciacca.
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Fragments of temporal artery obtained by surgical biopsy from 3 patients suffering from Horton arteritis were employed for immunopathologic studies by direct immunofluorescence. In 2 of the cases, granular deposition of IgM, C1q and C3 but not of albumin were observed in the wall of vasa vasorum of the temporal artery. Elution techniques determined the disappearance of the immunoreactants. In one case in which biopsy fragments of temporal artery were obtained prior to and after steroid treatment it was observed that IgM and complement, previously present, disappeared after such treatment. The data reported indicate that indeed immunologic factors play a role in the pathogenesis of the disease and that the immunoreagents present on the wall of vasa vasorum are not evidence of increased vascular permeability but indicate an active immunologic process which takes place in them.
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Recording of His bundle potentials by means of non invasive technique was first obtained in 1973. The Authors used a computerized, high resolution cardiograph to study 26 patients, 17 males and 9 females, mean age 57.15 +/- 21.79 years. H wave could be identified and therefore H-V interval could be calculated in 19 patients (73%). H wave identification is based on its morphological differentiation from other bioelectrical signals present in P-Q interval and on its repeated presence in all, or at least in the largest number of the six available leads. This technique, based on averaging process, is very useful in depistage of acute and chronic A-V conduction troubles.
In a double-blind investigation N-methyl-N-(beta-hydroxyethyl) guanidine O-phosphate (creatinol O-phosphate, COP) was checked versus a reference substance (solvent of COP) on volunteers affected by ischemic heart disease with persistent ventricular premature beats (VPB). COP was able to reduce VPB by 50--100% in 85% of the volunteers treated with this drug. This fact and the virtual absence of side-effects of COP lead the authors to the conclusion that COP merits more extensive investigations in this field in view of its clinical employment alone or in association with specific antiarrhythmic agents.
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The Authors carried out a Rotavirus investigation on the stools of 6057 children admitted in the Department of Pediatric and Pediatric Gastroenterology of Catania University, during the years 1984-1988. The stool samples of 264 children were found positive for Rotavirus. While 204 children presented gastrointestinal symptoms with diarrhoea, 12 had subclinical signs, 26 presented only respiratory symptoms and 22 had no clinical symptomatology. Moreover 122 children with diarrhoea had associated respiratory manifestations. In this study the authors punctualized that: 1) the most interested age was the first year of life; 2) there was no evidence in seasonal variations; 3) the respiratory tract was involved in high percentage of children (59.8%); 4) a transient lactase deficiency was supposed in every children with watery diarrhoea, but it was demonstrated only in 21 (10.3%).