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Biomedical subjects

A Schussheim

Publications and source records attributed to A Schussheim.

15 recordsLinked to original sources

Gallbladder disease in children and adolescents.

A 20-year experience with gallbladder disease in 85 children and adolescents was reviewed. Sixty-five patients had idiopathic cholelithiasis and cholecystitis (group I); 20 patients had cholelithiasis and cholecystitis secondary to a predisposing disease or other pathologic diagnoses (group II). For group I patients, 100% were greater than age 12, 92.3% were female, 60% were overweight, 20% had a positive family history, and 27.7% had had a previous pregnancy. For group II patients, 60% were less than age 13, 45% were female, 15% were overweight, 5% had a positive family history, and none had previously been pregnant. Symptomatology in group I, but not group II, patients matched that seen in adults. Group I, but not group II, patients experienced delays in diagnosis. These data indicate that children and adolescents with gallbladder disease constitute two distinct populations and that idiopathic cholelithiasis and cholecystitis must be considered as a potential cause of chronic abdominal pain in otherwise healthy adolescents.

Adolescent↗

Antibiotic-associated pseudomembranous colitis in siblings.

Pseudomembranous colitis induced by antibiotics is not commonly diagnosed in children. Recent developments have clarified the pathogenesis and suggested that agents such as cholestyramine are therapeutically useful. Two siblings with pseudomembranous colitis were carefully studied and may serve to alert pediatricians to an approach to this entity.

Anti-Bacterial Agents↗

Lipoprotein-X and other tests in the diagnosis of obstructive jaundice in the infant.

The infant with elevated direct-reacting bilirubin levels requires an early specific diagnosis to identify those who would require early surgical intervention and those in whom the bilirubin levels will eventually return to normal. This study compares the accuracy of three tests: the serum lipoprotein-X (LP-X), the I131 rose bengal (IRB) excretion and the serum alpha-fetoprotein (AFP) in making a specific diagnosis in 15 patients. When used individually the accuracy of the tests varies from 56-100%. The LP-X and IRB excretion are more specific and when in agreement are 100% acurate in the diagnosis of the neonatal hepatitis syndrome (NHS) or extrahepatic biliary obstruction (EHBO). This study suggests that both the LP-X and IRB excretion should be used in the investigation of the infant with conjugated hyperbilirubinemia.

Biliary Tract Diseases↗

Radionuclide diagnosis of bleeding Meckel's diverticulum in children.

The preoperative diagnosis of rectal bleeding due to Meckel's diverticulum in children has major difficulties when only standard clinical and radiographic technics are utilized. During the past three years we have done 70 studies with Tc99m pertechnetate for this suspected diagnosis using scintillation camera imaging and computer analysis. Five positive cases were identified and all verified at surgery. No false positives were noted. We believe this to be a safe and available procedure that should be considered a primary diagnostic modality in the investigation of young children with suspected bleeding Meckel's diverticulum.

Child↗

"Rectal ears".

"Rectal ears," transitory protrusions of the rectum into the internal inguinal rings, were observed in a 16-month-old girl who also had "bladder ears." Inguinal hernias were not present. The etiology and significance of "rectal ears" has not been determined.

Female↗