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Biomedical subjects

A Schrey

Publications and source records attributed to A Schrey.

At least 37 records · Page 2Linked to original sources
PubMed1981

[Combination of beta-receptor blocking agents and saluretica in outpatient treatment of hypertension. Results of a comparative study (author's transl)].

In a randomized single-blind study a comparison was made between the blood pressure lowering effect and the tolerance of two different combinations of beta-blockers and diuretic agents, one of the combinations being given in a sustained-release form. The study was made in 60 out-patients suffering from hypertension of the severity degrees I and II (WHO). The blood pressure reduction achieved as well as the diminution of the increase in heart rate and blood pressure under ergometric load proved to be almost equal in both groups. The number of patients whose blood pressure was normalized by the end of the study was larger in the group treated with Cardiotensin. The influence on laboratory parameters was only minimal and without clinical relevance. Both preparations have generally been well tolerated and exhibited an equal duration of effect.

Benzothiadiazines↗
PubMed1980

[Low diuretic dosage in a beta blocker-diuretic combination].

Thirty outpatients with arterial hypertension were treated for eight weeks with a daily dose of one tablet of Cardiotensin, taken after breakfast. The compound contains 100mg bupranolol, 10mg bemetizide and 20mg triamterene. Drug therapy was preceded by a one-week placebo washout period. Within two weeks of treatment, systolic and diastolic blood pressure had reverted to normal in 26 of the patients. At the end of the observation period, 4 patients still had diastolic pressure values of more than 100 mm Hg. Ergometer stress testing revealed clear-cut diminution of blood pressure and heart rate elevations following the medication. Serum potassium levels were not influenced by the drug. Under the mentioned dose regimen there were no changes in serum uric acid, creatinine, and glucose concentrations. Tolerability was generally good.

Administration, Oral↗