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A Scherrer

Publications and source records attributed to A Scherrer.

97 records · Page 6Linked to original sources

Hepatic metastases from leiomyosarcoma: MR features with histopathologic correlation.

BACKGROUND: To determine the magnetic resonance (MR) imaging features of hepatic metastases from leiomyosarcoma and determine the pathologic basis for the MR appearance of these neoplasms. METHODS: MR examinations of eight patients with a total of 16 hepatic metastases from leiomyosarcoma were retrospectively reviewed. Hepatic metastases originated from a primary gastrointestinal (n = 6), uterine (n = 1), or retroperitoneal (n = 1) leiomyosarcoma. Correlation between MR features and pathologic findings was performed in 11 metastases from which histologic material was obtained. RESULTS: Among the 10 metastases seen on T1-weighted MR images, nine were homogeneous and one was heterogeneous. The latter contained areas of necrosis and hemorrhage on pathologic examination. Among the 16 metastases seen on T2-weighted MR images, 12 were well delineated and completely homogeneous, with a marked hyperintense signal ("hemangiomalike" pattern). These neoplasms were composed of smooth fibrous tissue without macroscopically visible areas of necrosis on pathologic examination. The remaining four metastases were heterogeneous and contained varying degrees of necrosis and hemorrhage or gelatinous tissue. CONCLUSION: A hemangiomalike pattern is the most common feature on T2-weighted MR images. We found that homogeneous hyperintensity of hepatic metastases from leiomyosarcoma on T2-weighted MR image does not reflect cystic changes.

Adult↗

Differentiation between hepatic cavernous hemangioma and malignant tumor with T2-weighted MRI: comparison of fast spin-echo and breathhold fast spin-echo pulse sequences.

PURPOSE: The goal of our study was to compare a T2-weighted breathhold fast spin-echo (BHFSE) technique with T2-weighted nonbreathhold fast spin-echo (FSE) technique for characterizing cavernous hemangioma of the liver and differentiating this entity from malignant tumor. MATERIALS AND METHODS: Eighteen patients with cavernous hemangiomas and 18 patients with malignant hepatic tumors were studied with T2-weighted MRI with a nonbreathhold FSE technique with and without fat suppression and with a BHFSE technique without fat suppression. Hepatic lesions were analyzed quantitatively using signal intensity (SI) and contrast-to-noise (C/N) ratio. In addition, images were qualitatively compared for accuracy in characterizing hepatic lesion. RESULTS: Quantitatively, hemangioma had significantly higher SI and C/N ratios than did the malignant tumor on every pulse sequence (P < 0.01). Qualitatively, all malignant tumors were correctly categorized; differentiation between cavernous hemangioma and malignant tumor was impossible in three cases of cavernous hemangioma with the three pulse sequences (92% accuracy, 100% sensitivity, and 83% specificity). CONCLUSION: T2-weighted FSE and BHFSE MRI shows comparable levels of accuracy for differentiating between hepatic cavernous hemangioma and malignant tumor. Because overlap may exist using quantitative measurement, morphologic patterns must be carefully analyzed, supporting that quantitative analysis and morphologic evaluation are complementary.

Adult↗

Focal nodular hyperplasia of the liver: assessment of hemodynamic and angioarchitectural patterns with gadolinium chelate-enhanced 3D spoiled gradient-recalled MRI and maximum intensity projection reformatted images.

PURPOSE: Our goal was to determine the relative merits of gadolinium chelate-enhanced 3D spoiled gradient-recalled (GRE) MRI versus maximum intensity projection (MIP) reformatted images in assessing the morphologic, hemodynamic, and angioarchitectural patterns of focal nodular hyperplasia (FNH) of the liver. METHOD: Ten consecutive patients with 10 FNHs had prospectively gadolinium chelate-enhanced 3D spoiled GRE MRI (TR/TE/FA = 10.1/1.9/30) of the liver at 1.5 T. Gadolinium chelate-enhanced 3D spoiled GRE source images and MIP reformatted images were separately analyzed with respect to morphologic and hemodynamic features and angioarchitectural patterns by two independent readers. RESULTS: Gadolinium chelate-enhanced 3D spoiled GRE source images and MIP reformatted images showed the most intense degrees of enhancement of FNH during the arterial phase of hepatic parenchymal enhancement in all cases. Gadolinium chelate-enhanced 3D spoiled GRE source images were superior to MIP reformatted images for the assessment of morphologic features of FNH (p < 0.02). MIP reformatted images were superior to the corresponding source images for showing the main branches of the hepatic artery, an arterial branch going to the FNH, and a small artery within the FNH radiating to peripheral areas (p < 0.05). There was excellent agreement between the two observers for analysis of the MIP reformatted images (p < 0.05). CONCLUSION: The combination of gadolinium chelate-enhanced 3D spoiled GRE source images and MIP reformatted images allows the analysis of morphologic, hemodynamic, and angioarchitectural patterns of FNH of the liver. Further study and comparison with currently applied strategies will determine the value of these two techniques for diagnosing FNH of the liver.

Adult↗

[The compression syndrome: A revaluation of the value of postural angiography (author's transl)].

A total of 136 patients with a compression syndrome of the upper limb were examined systematically by selective dynamic angiography as developed by the Hôtel-Dieu Hospital in Montreal. The method consists of given multiple injections of a contrast medium with the patient's arm in thirteen different positions. This retrospective study demonstrated that this method carries very little risk and is well-tolerated by the patients. Conclusions are drawn from a comparative statistical analysis of the angiographic results and the therapy chosen. The practical value of the examination is not to confirm the anatomical site of the compression but to evaluate the characteristics of the stenosis before a decision is made whether to operate. In this respect, the positions in which the patient is sitting down and the arm is in abduction are those in which a difference is found between those patients operated upon and those given medical treatment, which is a point in favour of this particular procedure.

Adolescent↗

[Pitfalls of the dorsal decubitus in aortography].

The use of the prone position in aortography improves the visualization of the anterior wall of the aorta. This is supported by observation of an obstructed aortobifemoral by-pass and seems interesting in the study of aneurysms. More often, it is useful in case of decreased blood flow or increased local turbulence.

Aortography↗

[Is the barium enema preparation a good preparation for echography?].

A comparative study of 50 patients without previous preparation and 50 who were prepared by a barium enema and low residue diet demonstrated that this method of preparing for ultrasonography improved visibility of the pancreas and the overall quality of the examination. However, the difference in patients with or without previous preparation was not sufficient to justify its routine use.

Anthraquinones↗