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Biomedical subjects

A Scherrer

Publications and source records attributed to A Scherrer.

At least 73 records · Page 4Linked to original sources
PubMed1990

CT of malignant anal canal tumors.

Radiation therapy of malignant neoplasms of the anal canal has promising results in the majority of patients if the disease is limited at initial diagnosis. Computed tomography (CT), especially when performed with contrast material injected intravenously, is valuable in the pre- and posttreatment assessment of the anorectal musculature and perirectal nodes. The authors review the anatomy of the anorectal area and their experience with CT evaluation of anal canal cancer in a series of 26 patients. They also discuss their experience with treatment of this cancer in a series of 48 patients.

Anal Canal↗
PubMed1989

[Diagnosis of disorders affecting hollow intra-abdominal organs].

Modern imaging methods, including ultrasonography, computerized tomography and magnetic resonance imaging, add considerably to the information provided by the classical exploratory methods for hollow intra-abdominal viscera. They evaluate the size of these viscera and especially their wall and they are particularly useful when the lesion is transparietal, submucosal or even sub-adventitial. They also detect abscesses originating in the gastrointestinal tract, measure the extent of tumoral expansion beyond the mucosa and reveal intra-abdominal abnormalities associated with the lesions. The new methods, therefore, are very useful and often indispensable as a complement to other methods used to explore the digestive tract.

Gastrointestinal Diseases↗
PubMed1989

[Value of a score using clinical and biological variables for determining the benignity or malignancy of a hepatic mass].

The purpose of this study was to show that clinical and biological data can help in the diagnosis of benignity and malignancy in liver tumors seen on ultrasound. Three hundred and ninety-four patients with liver masses detected by ultrasound (270 malignant, 124 benign) were prospectively studied. Clinical and biological data were tested by univariate and multivariate analysis. The most important variables were gamma-glutamyl-transferase, sedimentation rate, known primary cancer, proven cirrhosis, abnormal abdominal palpation, ascites and weight loss. A regression model was used and a score was defined with these variables. Using this score, 94.8 p. 100 of the liver masses were accurately classified as benign and malignant tumors.

Diagnosis, Differential↗
PubMed1987

[Aid to the clinical and biological diagnosis of malignancy in a nodular hepatic image discovered by echography].

When ultrasound examination of the upper abdomen detects a liver nodule, the malignancy of this lesion must be discussed. If past history of cancer is known, a benign lesion cannot be excluded. Conversely, if the examination is performed without a history of cancer, we must raise the possibility of a malignant lesion. We attempted to demonstrate that the simple clinical and biological findings allow, if well used, a diagnosis of malignancy or benign nature, rather than performing further investigations, sometimes costly or invasive. We therefore compared three different methods: the well known bayesian diagnostic process; the multivariate analysis using logistic regression model; the Decision Theory, constructing a binary discrimination tree. The three methods lead to approximately the same rate of well classified patients (93 to 95%). Advantages and disadvantages are discussed.

Analysis of Variance↗
PubMed1986

[Radiologic surveillance of irradiated glomal tumors].

A favorable clinical result was obtained in 10 patients with jugular glomal tumors treated by external radiotherapy (approximately 50 Gy), alone or combined with surgical treatment, and preceded in some cases by embolization. Radiologic review examinations showed complete stability of lesions without bone reconstruction phenomena, in spite of a decrease in tympanic mass and regression of functional symptoms.

Adult↗
PubMed1985

Sonographic and computed tomographic evaluation of intrahepatic calculi.

Intrahepatic calculi in non-Asian patients were studied by sonography and computed tomography (CT). Three patients were studied by CT cholangiography also. In two cases, the calculi were consecutive to Caroli disease, and in two others, the biliary stones were formed proximal to a stenosis of a previous surgical anastomosis. Five patients spontaneously developed intrahepatic calculi. All sonograms were abnormal. Image specificity was good, even when bile ducts were not dilated, if appropriate technique allowed identification of a double-arc-shadow pattern. Sonography strongly suggested the diagnosis in eight patients and was nonspecific in only one. On CT, calculi had various densities, and they were not visible in two patients. CT cholangiography was not particularly helpful. Finally, CT added little more information when performed after sonography. Both examinations strongly underestimate the number of stones, and direct cholangiography remains indicated if surgery is planned.

Adult↗
PubMed1985

[Glomus jugulare tumors. Possibilities of radiotherapy].

From 1964 to 1981, twelve patients with glomus jugulare tumors involving bony lesions of base of skull were treated by high energy radiation. Ten patients presented cranial nerve pairs paralysis. Conventionally fractionated doses of 45 to 60 Gy were applied, and 11 of the 12 patients were alive and clinically stable after follow up for between 3 and 20 years. One patient died of an intercurrent infection after 16 years. Strict irradiation technique is essential to avoid principally neurologic complications. Favorable results after radiotherapy were obtained in extensive tympano-jugular forms.

Adult↗
PubMed1985

[Metastases of breast angiosarcoma. Apropos of 2 cases].

Two patients with breast angiosarcoma and hepatic and splenic metastases developed a hemoperitoneum confirmed by ultrasound and CT scan imaging. This complication has further adverse effects on the already extremely poor prognosis of this disease.

Adult↗
PubMed1985

[Value of the sitting position for studying suprahepatic veins by ultrasonography].

Ultrasound imaging of suprahepatic veins was conducted in 50 patients in the sitting and lying down positions and under the same respiratory conditions. Results showed that the sitting down position was frequently useful during exploration of suprahepatic veins, and it should be performed whenever visibility in the lying down position in unsatisfactory.

Hepatic Veins↗
PubMed1984

[Evaluation of vascular surgery with digital subtraction angiography. A study of 127 patients].

We have performed digital subtraction angiography (DSA) on 127 patients treated by vascular surgery. This technique was easily and safely performed in outpatients, without any complication. Our experience indicates that DSA is accurate for post operative evaluation in 96% of cases. In digestive arterial surgery, some examinations (3.3%) are insufficient. Distal run off is usually well seen, everywhere, except in kidneys. There is a good correlation between angiographic results and clinical status. However, significant abnormalities were discovered in 5% of cases without any clinical signs. Digital intravenous angiography is a safe and mildly invasive procedure for postoperative evaluation of vascular surgery.

Angiography↗
PubMed1984

[Heterogeneous steatosis. Echographic aspects].

Heterogeneous fatty degeneration of the liver was detected in 8 patients by ultrasound recordings, and confirmed by biopsy and the subsequent course. The etiology was alcoholism in most cases. Elevated transaminases and gamma GT were associated with modifications in hepatic ultrasound images. Foci of liver fatty degeneration were hyperechogenic, usually with clearly defined outlines, and were segmental, polygonal or rounded, and lacking mass effects. This condition requires differentiation from primary or secondary liver tumors, and can be confirmed by a CT scan and biopsy of a hyperechogenic zone found on ultrasonographic images strongly suggestive of the lesions.

Adult↗
PubMed1984

[Modulated filtration for routine standard thoracic films].

A new system is described for the filtration of routine posteroanterior chest films. The apparatus consists of a sliding support and two filters of different thicknesses and slit widths. The whole equipment, filter and sliding support as described is simple in use, and allows correct centering and a choice of two options of modulation as a function of morphology of patients examined.

Humans↗