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Biomedical subjects

A Santini

Publications and source records attributed to A Santini.

At least 91 records · Page 5Linked to original sources
PubMed1985

A suggested role for polymorphonuclear leukocytes in the perpetuation of periapical disease.

During the course of an investigation of endodontic materials using subcutaneously implanted human roots in rats and guinea pigs, it was noted that in areas of the root canal which had not been reamed polymorphonuclear leukocytes had migrated into the dentinal tubules. It is suggested that irritation of the periapical tissues may be mediated by these polymorphonuclear leukocytes. Therefore, the occlusion of dentinal tubules which may be exposed to periapical exudate may be of prime importance in endodontic treatment.

Animals↗
PubMed1984

[Update on the subject of trophism and liver regeneration].

Present knowledge of hepatic trophism and regeneration after partial resection of the parenchyma is reviewed. The importance of the various factors influencing hepatic regeneration (so-called hepatotrophic factors) is stressed by examining the most interesting data reported in the literature. In particular, an attempt is made to classify such factors according to their origin (e.g. hepatic or extra-hepatic) and specificity of action. A brief discussion of the clinical implications of this research and current treatment for acute and chronic hepatic insufficiency, with particular reference to the latest surgical techniques, closes the paper.

Epidermal Growth Factor↗
PubMed1984

The enzyme immunosorbent assay (ELISA) for serologic diagnosis of toxoplasmosis in pregnancy.

The enzyme-linked immunosorbent assay (ELISA) is simple, quick, and inexpensive, characteristics that make it particularly suitable for large screening programs. We compared the results obtained by ELISA with those obtained by immunofluorescent antibody test (IFAT), indirect hemoagglutination test (IHAT), and Sabin Feldman Dye test in a group of 105 pregnant women in the course of a screening for toxoplasmosis. Prevalence of IgG antibody titers were not significantly different. ELISA results were particularly close to those of the reference tests (IFAT and Dye test).

Adult↗
PubMed1983

ELISA antibodies to cytomegalovirus in pregnant patients: prevalence in and correlation with spontaneous abortion.

Prevalence of seroimmunity to cytomegalovirus (CMV) infection was tested by detecting ELISA IgG antibodies in 230 pregnant subjects from low socioeconomic backgrounds. Seroimmunity increased from 64.3% to 92.0% between the ages 15-20 and 35-40. Furthermore, ELISA IgM antibodies were detected during hospitalization in a group of 56 women whose pregnancies ended in spontaneous abortion and in a paired matched-control group. The overall percentage of IgM-positive reactions was 5.35% in the group with abortion. The percentage for only second trimester abortions amounted to 18.75%. There was no IgM-positive reaction in the control group.

Abortion, Spontaneous↗
PubMed1982

[Intestinal mechanisms of compensation and morphologic and functional adaptation after resection of bypass].

The intestine's ability to adapt following extensive resection is well known, and includes augmentation in calibre and the thickness of the wall, increased villus height, changes in motility, and qualitative and quantitative alterations in the flora. Positive identification of the mechanisms through which this morphological and functional adaptation takes place still forms the subject of research. An account is given of the latest views concerning the way in which compensation of the intestine takes place after resection and by-pass surgery.

Adaptation, Physiological↗
PubMed1982

[Scope and limitations of the surgical treatment of diabetes].

A brief account is given of the current knowledge, experiments, and clinical findings concerning the surgical management of diabetes. The aim of all treatments, from conventional pancreas transplant to the sophisticated transplantation of islets and foetal pancreas, and a subject with its own special features, namely intestinal by-pass, is to relieve the patient from insulin management, which, while it increases his survival, does not defend him from possibly fatal vascular complications. Though far from providing a final solution, each of the topics dealt with provides an example of the way research and clinical practice continue to offer reasons for the experimentation of new therapeutic techniques.

Diabetes Complications↗
PubMed1981

[Euglycemizing effect of partial jejuno-ileal resection in rats treated with streptozotocin].

Resection of about 50% of the small intestine was performed in rats diabetised with streptozotocin. The first results show that this operation leads to normalisation of sugar metabolism that is partly referable to partial malabsorption, but above all to loss of weight. Current knowledge with regard to the relation between diabetes and obesity is discussed and an account is given of the modern surgical approaches to the treatment of major obesity. Lastly, the suggestion is made that limited digestive bypass may be indicated in cases of insulin-independent diabetes where weight loss and control of blood sugar cannot readily be achieved by conventional medical management.

Animals↗
PubMed1980

[Echography in renal tumors].

Echography is highly important today for the identification and differentiation of renal diseases. It also enable target biopsy of identified lesions to be carried out, thus making for precise histological diagnosis. Indications and results of echography in the diagnosis of 97 cases of suspect masses of renal origin consisting of cysts, hydropyonephrosis, tumours, multicystic and polycystic kidneys are considered. Overall diagnostic accuracy was 92.7%. The features pointing to differential diagnosis of individual lesions and the method of examination, based on the use A and B Scan with grey scale are described. It is concluded that, with their high diagnostic accuracy and non-invasivity, scanning techniques represent an indespensable tool for the diagnosis of renal masses.

Humans↗