[Solid neoplasms associated with multiple myeloma].
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Humans↗
Biomedical subjects
A Salud
Publications and source records attributed to A Salud.
[Symptomatic hypomagnesemia in a patient treated with cisplatin].
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Adult↗
[Treatment with interferon of systemic Langerhans-cell histiocytosis in an adult].
We report an adult patient with systemic Langerhans' cell histiocytosis (LHX), who was refractory to multiple chemotherapy courses and in whom a partial clinical and biological 3-month remission was achieved with alpha-2-interferon. The patient's response was associated with an increase in the rate of natural killer cells and to a return to normal of the H/S T-lymphocyte ratio. Immunological abnormalities have been reported in this condition, and it is now accepted that the most important one is a decrease in suppressor lymphocytes. However, it is not known whether these abnormalities are endogenous or exogenous. The experience with modifiers of the biological response for the treatment of LHX is scanty, but the probable immunological pathogenesis of the condition justifies a therapeutic trial of those agents in patients not responding to conventional therapy.
Adult↗