Effects of antimonial therapy for canine leishmaniasis on antibody titer.
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Biomedical subjects
Publications and source records attributed to A Sainz.
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OBJECTIVE: The study examined factors that help determine a good or poor fit between the psychosocial support needs of hospitalized patients and the hospital's discharge plan. METHODS: The Mount Sinai Discharge Planning Inventory was completed weekly for 494 consecutive admissions to the hospital's adult inpatient psychiatric units. The resources that patients brought with them into the hospitalization in the areas of housing, entitlements, daily activities, and psychiatric treatment were recorded as well as the resources that would constitute an optimal discharge plan. Good or poor fit was operationally defined by the match between the optimal, first-choice plan and the implemented discharge plan. RESULTS: One-third of admissions were found to have an optimal fit on admission in all resource categories studied. For patients who entered the hospital with suboptimal resources, discharge planing was significantly more likely to establish clinically relevant psychiatric treatment options and to strengthen daily living activities than to change housing resources. Certain diagnoses and a history of drug abuse, criminality, violence, and treatment noncompliance were associated with poorer fits with first-choice disposition options. CONCLUSIONS: The Mount Sinai Discharge Planning Inventory provides a method to systematically evaluate discharge planning by tracking progress toward securing relevant posthospital care and support.
Hematological and plasma chemistry parameters were measured in 129 juvenile white storks (Ciconia ciconia), either wild or captive bred, April to June 1994. Wild storks were members of a colony in the Lozoya River Valley, Madrid, Spain. Red blood cells count, packed cell volume and hemoglobin increased significantly with age. White blood cells count, lymphocytes count and platelets decreased with age. Total solids, total proteins, fibrinogen, albumin, alpha, beta, gamma-globulins and urea increased with age. Differences between captive and wild birds were not notable.
The results of a histological and immunohistochemical study of endoscopic colon biopsies of dogs with plasmacytic-lymphocytic colitis are reported. The histological study revealed that a characteristic infiltrate rich in lymphocytes and plasma cells was seen within the lamina propria in all the biopsies. The immunohistochemical investigation suggests that IgG is the major antibody in the immune response of dogs with plasmacytic-lymphocytic colitis.
The parameter deceleration vs. acceleration (dc/ac) as derived from the instantaneous peak velocity is obtained by dividing the descending and ascending slopes of plotted velocity curves. Blood velocities were recorded with a specially designed continuous-wave ultrasonic Doppler unit which provides: the instantaneous peak velocity, the instantaneous mean velocity, the acceleration, and an indication of volume flow. A physical meaning to the dc/ac parameter is given through an analysis, based on an electrical model, of a small portion of an artery. This gives a simple relationship which only takes account of the assumed vascular resistances. Measurements were performed in 67 male subjects; 39 were normotensive control subjects and 28 had established moderate hypertension. In both groups there was an increase of dc/ac in passing from the supine to the erect position, the increase being more accentuated by hypertension. The variation of dc/ac with age was significantly different in both groups. The results suggest that this parameter is a sensitive indicator of variations in vascular reactivity and as an indicator of structural changes in the arterial wall.
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A new method of measuring blood flow velocity and acceleration using analogue and phase locked loop techniques is described. Instantaneous peak velocity, instantaneous mean velocity and acceleration can be obtained on-line and displayed on simple recording systems.
An easily constructed, low-priced, simple, and reliable module to obtain stroke volume and cardiac output by analog integration of aortic blood flow velocity signals is described. Rapid data analysis of physiologic and pharmacologic cardiovascular responses in dogs is greatly facilitated by on line computation of these parameters.
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This paper reports the clinicopathologic responses of 93 dogs with spontaneously occurring ehrlichiosis to 3 different treatment protocols. Thirty-two dogs were treated with doxycycline (10 mg/kg/day for 28 days), 31 were treated with imidocarb dipropionate (5 mg/kg given 15 days apart in 2 separate injections), and 30 were treated with both drugs simultaneously, at the doses as specified. The dogs underwent clinicopathologic evaluation before and after treatment, and were examined periodically during the 24-month period after the treatment. No differences were found in the clinical responses among the dogs in the 3 treatment groups. As for the clinicopathologic response, in spite of the fact that at the end of the study the results obtained with the 3 protocols were similar, the platelet count and serum protein electrophoresis results returned to normal more slowly in dogs that received imidocarb dipropionate as compared to those given the other 2 treatments.