Management of alternating exotropia.
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Biomedical subjects
Publications and source records attributed to A Said.
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In this work 60 male albino rats were subjected to a feeding experiment aimed to study the influence of protein free and reduced diets on normal function of rat testes. It was shown that the PEM exerts adverse effects on testicular function, the nature and severity of these effects depend on the duration of the deficiency state. Histological examination of rat testis, revealed that the spermatogenesis is arrested at spermatogonium stage in rats fed on protein free diet, and at primary and secondary spermatocyte stage in rats fed on normal but reduced diet.
The level of total amino acids was determined in plasma and urine in cases suffering from ocdematous forms of PCM before and after receiving a single dose of each of cysteine, tryptophan and lysine. The increase in plasma amino acids following dosing was less in malnourished cases than in controls. Fasting urinary amino acid content in malnourished subjects was higher than in controls and so was also the ratio of urine amino acids collected after dosing to the fasting level. As the study revealed that protein depletion inhibits intestinal absorption and tubular reabsorption, parenteral administration of amino acids is recommended during treatment to escape intestinal loss. Excess oral protein should be given in food to compensate for losses via the gastro-intestinal and renal tracts.
Enzymuria observed in PCM, especially in severe cases, does not seem to be a simple reflection of the increased serum values and suggests renal involvements. A number of factors among which are :- lowered clearance threshold for certain enzymes as well as rapid wear and tear or renal cells seem to participate in the causation of such enzymuria. Urine enzyme analysis may reflect the extent and state of renal pathology among different forms of PCM.
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