Biomedical subjects

A Sack

Publications and source records attributed to A Sack.

12 recordsLinked to original sources

PubMed2004

Changes in negative symptoms and EEG in schizophrenic patients after repetitive transcranial magnetic stimulation (rTMS): an open-label pilot study.

The effects of repetitive transcranial magnetic stimulation (rTMS) on schizophrenic negative symptoms (NS) and EEG topography were investigated in this pilot study. 10 patients with predominant NS were treated with 10 Hz rTMS over the left dorsolateral prefrontal cortex for 5 days. For NS ratings, the Scale for the Assessment of Negative Symptoms (SANS) was used. Both ratings and EEG recordings were obtained pre- and post-rTMS. Electrical activity changes were computed by Low Resolution Brain Electromagnetic Tomography. SANS showed an improvement after rTMS, from 49.0 (SD: 10.7) to 44.7 (SD: 11.8) (means). EEG frequency bands were changed fronto-temporally (right) and were mainly decreases in delta- and beta- and increases in alpha1-activity, as well as decreases in beta-activity in the temporal and parieto-occipital regions (left). Although we are aware of the limitations of this study, we assume a slight improvement in NS. The EEG findings refer to a possible neurophysiologic correlate of their improvement after rTMS.

Adult↗

PubMed2001

[Reduction of nosocomial infections by a public health quality management concept in surgical patients. 1: Significant reduction of a high initial rate].

A successful introduction of surveillance of NI and quality circles for prevention of infection was achieved in hospital A. The major requirements therefore are according to our experiences determination of the topics of the quality circles by the participants themselves, interest and engagement for the work of the quality circles and the realization of ideas, support by the hospitals' management, acceptance of this work by the wards, continuous evaluation of the work of the quality circle. Often the most important problem was not identification of weaknesses and creating of possible solutions, but putting the ideas into practice on the wards. This was the case for problems in the field of care as well as in the responsibility of physicians. Altogether a significant 42% reduction of nosocomial infections was achieved.

Cross Infection↗

PubMed2000