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A Sacerdote

Publications and source records attributed to A Sacerdote.

35 records · Page 2Linked to original sources
PubMedDate not supplied

Nifedipine reduces postexercise proteinuria in young volunteers.

Previous studies have demonstrated that it is possible to prevent postexercise proteinuria with angiotensin-converting enzyme inhibitors. To determine whether calcium antagonists have the same effect, 40 young healthy volunteers underwent maximal aerobic exercise with and without nifedipine 10 mg per os 1 h before the first or second trial. Urinary excretion of albumin (UAE), transferrin (UTE) and alpha 1-microglobulin (UME) were examined before and after each trial. UAE, UTE and UME were significantly increased after exercise. Nifedipine significantly decreased UAE (p = 0.001) and UTE (p = 0.02) after exercise, and slightly decreased the maximal work load and the basal excretion of albumin. UME was unchanged. Therefore, the results of this study demonstrate that nifedipine administration before exercise significantly reduces postexercise proteinuria.

Adult↗
PubMedDate not supplied

[Comparative assessment of arterial blood pressure and body composition in athletes practicing physical culture and in obese subjects].

The relationship between body weight excess and hypertension has been widely demonstrated. Some body-builders can reach an important body weight excess because of the skeletal muscle hypertrophy; their body mass index is comparable to that of obese subjects, although body fat excess is responsible for overweight in the latter. Blood pressure, fasting plasma glucose and insulin, Na+, K+, Ca++ urinary excretion have been compared in three groups of young males: 1. body builders with BMI greater than 27; 2. obese subjects with BMI greater than 27; 3. normal subjects with BMI less than 25. Systolic blood pressure was similar in body-builders and obese and significantly higher than in the control group. Diastolic blood pressure, fasting plasma glucose and insulin were similar in normal subjects and in body-builders and significantly lower than in obese subjects. Although our results confirm the relationship between increased diastolic blood pressure, hyperinsulinemia and body fat excess, the finding of increased systolic blood pressure suggests caution in body-building, because systolic hypertension has been demonstrated to be a risk factor for vascular diseases.

Adult↗