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Biomedical subjects

A S Thambiah

Publications and source records attributed to A S Thambiah.

At least 19 recordsLinked to original sources
PubMed1999

Clinical and mycological features of dermatophytosis in renal transplant recipients.

Dermatophytosis was detected in 42% of 100 renal transplant recipients screened, of whom 17% had the infection for more than 1 year. Tinea cruris and tinea corporis were the common clinical types observed. Tinea unguium presented as proximal subungual white onychomycosis (PSWO) in 3% of patients. The lesions in the majority were non-inflammatory, scaly and without central clearance. The commonest isolate was Trichophyton rubrum.

Adolescent↗
PubMed1990

Genetics of hairy ears in south Indians.

Of 500 individuals screened at the Out-Patient Clinic, Mycology Section of the Department of Dermatology, Government General Hospital, Madras, 83 adult males (16.6%) and two adult females (0.4%) had hairy ears. Family study in five probands (three males and two females) suggests an autosomal-dominant sex-limited inheritance of this entity, probably linked to the genes for beard hairs, which is peculiar to males in South India and Sri Lanka. There has been an increased incidence of diabetes mellitus in the affected group. A control study made in a similar population of 1030 (680 male and 350 female) individuals attending the general medical and surgical out-patient clinics revealed hairy ears in 23.1% (237 male adults and one female adult).

Adolescent↗
PubMed1988

Cutaneous trichosporosis.

Of 269 patients with cutaneous trichosporosis a majority of 170 (63.2%) showed the infection as intertrigo in the genitocrural and perianal areas. The predominant symptoms were itching and burning. Trichosporosis has been found to be less common in the other sites. Trichosporosis due to Trichosporon beigelii should be kept in mind as one of the differential diagnosis in cases of genitocrural intertrigo and other cutaneous infections by fungi and bacteria in the tropics.

Adolescent↗
PubMed1987

A clinico-pathological study of actinomycotic mycetomas caused by Actinomadura madurae and Actinomadura pelletierii.

Twenty seven cases of actionomycotic mycetoma caused either by Actinomadura madurae or Actinomadura pelletierii have been described. Infection by A. madurae has been more common than A. pelletierii. Left foot in A. madurae and right foot in A. pelletierii infections were involved more commonly in adult males, whereas right foot of the females was frequently affected in A. madurae infection. Large, soft, white grains in A. madurae and small, firm, red grains in A. pelletierii were consistently seen. Deep hematoxylin stained grains with scalloped margin and prominent eosinophilic club in A. madurae and such deep stained grains with smooth margin and horizontal cracks appearing as portions of a spherical mass in A. pelletierri were diagnostic. Large numbers of plasma cells and Russel bodies were also characteristic of A. madurae infection. Both the grains were stainable with Von Kossa method for calcium. Bone changes were similar in both the infections. Oral tetracycline produced soft tissue and bone resolution to almost normalcy in those who regularly consumed the drug any time from 2 to 6 years. Mild glucose intolerance, facial hyperpigmentation and urticaria were the side effects observed in a few. Two patients developed cataract following tetracycline therapy. The value of medical therapy with oral tetracycline in Actionomadura mycetomas is emphasized.

Actinomycetales↗
PubMed1984

Palmar melanotic macules. A sign of neurofibromatosis.

Multiple melanotic macules of varying sizes were present on the palmar surfaces of 42 of 50 consecutive South Indian patients with von Recklinghausen's disease. The histologic characteristics of the macules showed localized areas of fingerlike prolongations of the rete ridges with increased pigmentation of the basal cells. This epidermal change overlies a small neurofibroma accompanied by thick-walled blood vessels in the reticular dermis. A clinicopathologic correlation of these palmar melanotic macules constitutes yet another frequent and specific marker of classical neurofibromatosis.

Female↗
PubMed1984

Muscle invasion by Basidiobolus haptosporus.

Invasion of muscle tissue in addition to dermis and subcutaneous tissue by Basidiobolus haptosporus is reported in a 40-year-old female housewife. This infection followed intramuscular injection injury of the right gluteal region. Oral KI cured the condition completely in 6 months. Intramuscular implantation of B. haptosporus by the injection needle is the probable mode of infection in this case. Possible blood vessel invasion seen in histology suggests the possibility of dissemination of the fungus.

Adult↗