[Effect of vitamin D2 on the osseous capsule of the labyrinth of gravid and nursing rabbits and their progeny].
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Biomedical subjects
Publications and source records attributed to A S Kiselev.
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The statistics of population health and development of public health system is incomplete. Mortality values can be analyzed for 5-year intervals, while morbidity is represented for the following age groups: children, adolescents, adults aged 20-39 and 40-59 years. The authors suggest revising the structure and volume of statistical data on morbidity with regard for age and sex for 5-year intervals, which will help more reliably and correctly solve modern problems of public health.
Typical clinical features of nasal and paranasal sinus chondromas are discussed having in view 12 history cases. The authors give support to the concept that benign chondroma may transform to malignant neoplasm. Tumor relapses may occur if surgical intervention fails due to morphological abnormalities of the tumor. The tumor consists of lobules that may grow beyond the primary connective tissue capsule penetrating complex structures of the skull. Patients with nasal and paranasal chondromas need early and radical operation and a close follow-up with the purpose of detecting minor signs of recurrences and performing, if necessary, repeated operations until the tumor becomes incurable.
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The paper provides data on a comprehensive rhinological and x-ray examination of 201 patients suffering from optochiasmal arachnoiditis (OCA). Paranasal affection (as a rule polysinusitis) was disclosed in 75.6% of the examinees. The lesion occurred primarily in the sphenoidal sinuses and frequently combined with ethmoidal labyrinth and maxillary sinus involvement. Rhinological and x-ray symptoms in OCA are rarely prominent giving grounds to physicians for defining it as the syndrome of minor clinical signs. The latter hold importance for diagnosis which enables early cleansing of the paranasal sinuses in combined treatment of OCA.
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The authors analyze published data on various modifications of the specific leukocyte lysis test (SLLT) and their own findings on in vitro osmotic leukocytolysis caused by low-molecular nonelectrolytes (urea, glycerol, and glucose), and present the estimation of osmotic pressure of these agents' solutions in equimolar concentrations. In contrast to the specific effect of allergens, an osmotic component of nonspecific leukocyte lysis is considered. A universal approach to the choice of working doses of drug in SLLT is proposed: equimolar solutions of the allergens (chemical and medicinal compounds). The necessity of further theoretical and practical research of SLLT is validated.
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