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Biomedical subjects

A S Grove

Publications and source records attributed to A S Grove.

At least 37 records · Page 2Linked to original sources
PubMed1983

Detection of human papillomavirus DNA sequences in conjunctival papilloma.

Two histologically proven conjunctival papillomas (one from a 33-month-old boy and the other from a 28-year-old woman) were examined for the presence of papillomavirus by DNA molecular hybridization. The first case, a recurrent tumor known to be positive for papillomavirus structural antigen, demonstrated human papillomavirus DNA sequences that cross-hybridized to a human papillomavirus type 11 DNA probe. The second case, an initial tumor, which was negative for papillomavirus structural antigen, demonstrated no viral DNA sequences by hybridization.

Adult↗
PubMed1982

Computed tomography in the management of orbital trauma.

Computed tomography (CT scanning) is a valuable aid in the management of orbital trauma because it provides a method of visualizing tissues and objects of many different densities. CT scanning can be used to study orbital fractures in order to suggest the prognosis for improvement of ocular malpositions after surgery. The extent of fractures and the etiology of many soft tissue abnormalities can be determined by this technique. Foreign bodies can be accurately localized so that the approach to their removal can be planned.

Carotid Artery, Internal↗
PubMed1982

Mucoepidermoid carcinoma of the lacrimal gland.

Mucoepidermoid carcinoma is a tumor arising in the ductal epithelial cells of the salivary and lacrimal glands, containing both mucin-producing cells and epidermoid cells with various degrees of squamous differentiation. While mucoepidermoid carcinoma has been reported frequently in the salivary glands, 1,2 it has been infrequently reported in the lacrimal gland, 3-5 with a total of just nine cases found, to our knowledge; we are reporting two additional cases.

Adult↗
PubMed1981

Upper eyelid retraction and Graves' disease.

Ten upper eyelids of patients with lid retraction due to Graves' disease were treated by levator marginal myotomies. The most common clinical abnormalities were thickening and fatty infiltration of the levator, with adhesions to the orbicularis muscle and the orbital septum. Histologic examination of these tissues revealed collagen proliferation, striated muscle atrophy, and fatty infiltration. The technique and usefulness of levator marginal myotomy are described.

Adipose Tissue↗
PubMed1981

Rhinoscleroma with exophthalmos: a case report.

This is a report of a 20-year-old Nigerian man with a 15-year history of exophthalmos and nasal blockage caused by rhinoscleromatous. The diagnosis was made by histopathological examination of a biopsy specimen taken from the nasal passages. Despite protracted antibiotic therapy the patient experienced recurrent exophthalmos. Computerised axial tomography and sinus films showed the lesion to have invaded through the sinus passage into the orbit. Further histopathological examination of tissue removed at the time of surgical decompression also revealed rhinoscleroma. This appears to be the third report of rhinoscleromatous spread to the orbit.

Adult↗
PubMed1980

Levator lengthening by marginal myotomy.

A surgical procedure has been designed for lengthening the levator aponeurosis by two partial-width (marginal) myotomy incisions. This operation does not require complete division or disinsertion of the levator, Müller's muscle, or tarsus. No foreign materials or sclera need to be inserted into the lid. The procedure has been used to treat upper lid retraction due to ophthalmic Graves' disease and for eyelid reconstruction after resection of basal cell carcinoma that involves the lid margin. Since an anterior incision is made through the skin, adhesions between the levator aponeurosis and the overlying tissues may be divided in patients with Graves' disease.

Adult↗
PubMed1980

Hepatoma metastatic to the orbit.

A 69-year-old man with a history of cirrhosis of the liver had unilateral progressive proptosis without jaundice, abdominal pain, or gastrointestinal symptoms. Results of laboratory and radiographic studies were also normal. Orbital biopsy revealed hepatocellular carcinoma. Although hepatocellular carcinoma has often been shown to metastasize to the brain and often to the flat bones of the skull, to the best of our knowledge, this is the first histologically proven case of hepatoma metastatic to the orbit.

Aged↗
PubMed1980

CT and ultrasound in the diagnosis of cavernous hemangioma and lymphangioma of the orbit.

Eighteen cases of cavernous hemangioma and seven cases of lymphangioma of the orbit were evaluated with regard to contrast enhancement, hemogeneity, type of margin, anatomic location, and associated changes in he bone. Hemangiomas usually demonstrated homogeneous contrast enhancement, a relatively smooth margin, intraconal location, with occasional extension to the orbital apex, and focal bone expansion. Lymphangiomas showed either minimal heterogeneous or absence of contrast enhancement, irregular margins, and anterior and posterior locations. Ultrasonography of hemangiomas showed high amplitude and closely packed echoes from vessel walls adjacent to blood-filled spaces. Lymphangiomas had a similar ultrasound pattern, but with very wide separation of echoes due to larger fluid lakes.

Adolescent↗
PubMed1980

Eyelid retraction treated by levator marginal myotomy.

Upper eyelid retraction in patients with ophthalmic Graves' disease may be due to: (1) overaction of Müller's muscle; (2) overaction of the levator muscle; (3) contraction of the levator; and (4) subcutaneous adhesions anterior to the levator. A new operation is described to lengthen the levator by performing partial width (marginal) myotomies. If present, subcutaneous adhesions can also be divided during this operation. Histologic features of levators and Müller's muscles from patients with upper eyelid retraction are discussed.

Eyelid Diseases↗
PubMed1980

Orbital trauma and computed tomography.

Because computed tomography visualizes most soft tissues, foreign bodies, and bone details, it is an important supplement to conventional radiography in evaluating orbital trauma. A series of eight cases is presented to demonstrate the value of computed tomography. Several special techniques that enhance the usefulness of computed tomographic scanning are described.

Eye Diseases↗
PubMed1980

Melanomas of the conjunctiva.

Conjunctival melanomas are much less common than custaneous melanomas. Consequently, the classification and treatment of these mucosal tumors is more controversial than that of skin tumors. Conjunctival melanomas can be simply classified into tumors that are superficial and develop in a radial-growth phase, and those that are invasive and develop in a vertical-growth phase. By careful histological examination the maximum tumor thickness can be measured and the presence of the tumor within conjunctival epithelium, the substantia propria, or deeper tissues can be determined. Superficial tumors, tumors with a total radial-growth phase, tumors thinner than 0.76 mm., tumors confined to the conjunctival epithelium, and tumors near the corneal limbus seem to have a favorable prognosis. The fact that a conjunctival melanoma arises in an area of acquired melanosis, arises in association with a nevus, or arises de novo has not been definitely proved to be of prognostic significance. Treatment of conjunctival melanomas should be preceded by biopsy and histological confirmation of the diagnosis. Systemic evaluation should include examination of regional lymph nodes, chest roentgenograms, liver scans, and liver function tests. The eye and the complete conjunctival surface should be carefully examined, photographed, and drawn. The commonly accepted treatment of stage I melanomas of the skin or conjunctiva is surgical removal of the malignant tissue. Superficial and minimally invasive tumors near the corneal limbus may sometimes be excised with en bloc resection of the adjacent superficial cornea and sclera. Treatment of any malignant tumor must be somewhat individualized. Melanomas involving the fornices and eyelids may be treated by complete excision or by exenteration. Exenteration seems to be a reasonable plan in patients with extensive or bulky tumors. The role of prophylactic regional node dissection has not been established for patients with conjunctival melanomas. Similarly, adjunctive chemotherapy, immunotherapy, and hormone therapy are of unknown value in the management of stage I tumors of the conjunctiva. Cryotherapy and radiation therapy have been used only in small numbers of patients with conjunctival melanomas. The choice of these treatments instead of surgical excision in the management of such tumors should be highly selective.

Conjunctiva↗
PubMed1979

Orbital trauma evaluation by computed tomography.

Computed tomographic scans are useful for the evaluation of orbital trauma because they provide visualization of fractures, soft tissue damage, and embedded foreign bodies. Six cases are presented to demonstrate the usefulness of these studies in the evaluation of patients with a variety of injuries. By using both coronal and axial computed tomographic scans, orbital details can be studied with three-dimensional accuracy.

Female↗
PubMed1979

Giant dermoid cysts of the orbit.

Giant dermoid cysts of the orbit are developmental abnormalities that are usually found near the lacrimal gland in adults. The diagnosis of giant dermoid cysts can usually be established by radiographic studies and computed tomographic scanning. A surgical technique for the removal of these lesions with minimal complications is described in detail. Two cases are presented to demonstrate the methods used to diagnose and completely remove giant dermoid cysts with recovery of visual function and extraocular movements.

Adult↗