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Biomedical subjects

A Rutherford

Publications and source records attributed to A Rutherford.

54 records · Page 3Linked to original sources
PubMed1987

Electrophysiological demonstration of host cortical inputs to striatal grafts.

Adult rats received a unilateral injection of ibotenic acid into the striatum, resulting in an extensive loss of intrinsic striatal neurones. Transplanted striatal cells from embryonic day 14 rat foetuses grew well in the damaged tissue and approximately 6 months later brain slices were cut in such a way as to include the grafts and nearby cortical tissue. Electrophysiological recordings from the grafts showed typical extracellular responses to stimulation of the subcortical white matter. Thresholds and latencies for responses were similar in grafted and control striatum. The grafted cells, however, appeared to be subject to less collateral inhibitory control than normal striatal neurones. The similarities between the responses of grafted neurones and those in normal striatum suggest that corticostriatal connections reform after transplantation, which may be an important component in the behavioural recovery observed in similar animals.

Animals↗
PubMed1985

Fractures of the lateral humeral condyle in children.

I conducted a clinical review of thirty-nine fractures of the lateral condyle of the humerus in children and drew the following conclusions: (1) epiphyseal arrest is rare (it occurred in only one patient, despite malreduction in ten), and (2) fishtail deformity of the distal part of the humerus occurs commonly when malreduction is present. Only two poor results were encountered, both in patients in whom the reduction was grossly inadequate.

Adolescent↗
PubMed1983

Osteomyelitis of the symphysis pubis.

A case of osteomyelitis of the symphysis pubis caused by Streptococcus agalactiae with no identifiable predisposing factors is presented. The differentiation from osteitis pubis and the causative organism are discussed.

Female↗
PubMed1983

Footprints.

Explore the source record for details and available documents.

Child↗
PubMed1981

Stereophotogrammetry and relief photography in the assessment of foot disorders.

Expanded polyethylene foam (Plastazote) is used in the treatment of rheumatoid, diabetic, and leprotic foot disorders. This paper describes a diagnostic use for this material. Two photographic techniques combine to give vivid and quantitative representations of foot deformities which are easily applicable to clinical use. Relief photography uses illumination to create an illusion of solidity in a 2-dimensional photography. Stereophotogrammetry produces contour plots from stereopairs of photographs of the Plastazote footprint. After use the impressions are trimmed and slipped into the patient's shoes in the same way as any other foam insole.

Dermatoglyphics↗
PubMed1979

Should recurrent calcium oxalate stone formers become vegetarians?

The hypothesis that the incidence of calcium stone disease is related to the consumption of animal protein has been examined. Within the male population, recurrent idiopathic stone formers consumed more animal protein than did normal subjects. Single stone formers had animal protein intakes intermediate between those of normal men and those of recurrent stone formers. A high animal protein intake caused a significant increase in the urinary excretion of calcium, oxalate and uric acid, 3 of the 6 main urinary risk factors for calcium stone formation. The overall relative probability of forming stones, calculated from the combination of the 6 main urinary risk factors, was markedly increased by a high animal protein diet. Conversely, a low animal protein intake, such as taken by vegetarians, was associated with a low excretion of calcium, oxalate and uric acid and a low relative probability of forming stones.

Calcium↗
PubMed1979

Urinary tract stone disease.

Patients suffering from urinary stone are traditionally referred to a surgeon. Most are investigated only as far as establishing the site of the stone and its effect on renal function. Although a number of patients may require surgery, the majority pass the stone spontaneously and are discharged within a few days. If the patient has a recurrence, as most eventually have, it is not routine practice to establish the type of stone, screen for underlying disease, identify the urinary abnormalities or to institute preventive medical treatment. Although it was considered that surgery itself had something to offer in reducing the recurrence rate this is no longer generally held except in infected stone disease. Nevertheless it is still uncommon to involve a physician, and in particular a nephrologist, in the investigation and management of urinary stone-formers. Urinary stone disease still remains, to a large extent, outside the field of nephrology.

Bacterial Infections↗
PubMed1978

Neuronal and non-neuronal components in the overflow of labelled adenyl compounds from guinea-pig taenia coli.

Guinea-pig taenia coli preprations were pre-incubated in 3H-adenosine and the overflow of 3H-compounds to a superfusing medium was measured during transmural field stimulation in the presence and absence of tetrodotoxin. The fractional overflow of 3H-compounds on stimulation of taenia coli pre-incubated in 3H-adenosine at 10(-7) M was greater than after incubation at 10(-5) M. About half of the releasable store was blocked by tetrodotoxin. It is proposed that at lower concentrations, there is selective loading of a releasable store, while at higher concentrations thare is a greater loading of non-releasable stores, and that neuronal stores account for about 33% of the 3H-compounds released by transmural stimulation.

Adenosine↗
PubMed1977

Beef cattle productivity under traditional and improved management in Botswana.

A comparison of productivity over a 4-year period from indigenous type beef cattle under two production systems in Botswana is reported. The two systems are: the traditional system on unenclosed communal grazing (cattle post) and ranching within fenced paddocks. Calving percentages, 7-month old calf weight, calf mortality and post-weaning growth to 18 months of age under cattle post conditions were 46.4 per cent, 122.5 kg, 10.2 percent and 88.5 kg respectively. Corresponding figures for cattle on the fenced ranches were 74.0 per cent, 177.4 kg, 8.5 per cent and 105.8 kg. These results indicate overall productivity estimates of 51 and 120 kg of weaner calf per cow per year and 86 and 188 kg of 18-month old calf per cow per year for the cattle post and fenced ranch respectively.

Animal Husbandry↗