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Biomedical subjects

A Russo

Publications and source records attributed to A Russo.

At least 847 records · Page 47Linked to original sources
PubMedDate not supplied

[Colonoscopy in children: personal experience].

Since 1974, 162 colonoscopies have been performed on patients ranging in age from six months to 15 years. All examinations were done using adult endoscopes. Most of the exams were conducted either without any pharmacological preparation or after administration of benzodiazepine; in only 16 cases was general anesthesia without intubation (Ketamine) necessary. The most frequent indications for performing the exam were various types of anal bleeding, isolated, or associated with diarrhoea. The diagnosis made most frequently was of an isolated polyp (43 cases out of 162), localized almost exclusively in the rectum or sigmoid colon. The second most frequent diagnosis was of an inflammatory process (12 cases out of 162). It was noted that a large number of cases were found to be negative (73 cases out of 162), which may be explained by the fact that many cases of that age group involve acute processes healed when were examined.

Adolescent↗
PubMedDate not supplied

[Intracranial tumors during the first year of life: clinicopathologic study of 24 cases].

Brain tumors which manifest themselves neurologically in the first year of life can be declared "congenital". They are considered to be rare. Of a total of 440 central nervous system neoplasms in children, operated between 1951 and 1978, 24 (5,4%) congenital tumors were noted. The Authors report a clinical picture and the follow-up. The histology and topographical distribution of this series of tumors is compared to the literature data. The frequency of supratentorial tumors (15 cases; 62,5%) was much higher than that of infratentorial masses (9 cases); 37,5%). The high incidence of astrocytomas, choroid plexus papillomas and medulloblastomas is emphasized.

Brain Neoplasms↗
PubMedDate not supplied

Evaluation of integrated morpho-biological indicators in breast cancer.

A series of 71 patients undergoing surgery for primary breast carcinoma was prospectively studied in order to verify the relationships between clinical and pathological variables, proliferative indexes and DNA-ploidy. Significant correlations between proliferative indexes were found; conversely, DNA-ploidy showed no correlation with either PCNA/cyclin or AgNORs, but only with flow cytometry S-phase fraction (FCM-S) and IF-vimentin. In the 42 patients with a mean follow-up of 42 months, disease-free rate was best predicted by nuclear grade (p < 0.001), histological grade (p < 0.001), mitoses (p 0.001), IF-vimentin (p 0.002), FCM-S (p 0.002), PCNA (p 0.005) and Ag-NORs (p 0.007).

Adult↗
PubMedDate not supplied

[The extended middle cranial fossa approach: a morphometric analysis].

The extended middle cranial fossa (EMCF) approach calls for removal of the petrous bone from its subtemporal surface in order to well expose the internal auditory canal (IAC) and the posterior fossa dura (PDF) around its meatus, safeguarding, at the same time, all the important, closely related, anatomical structures (the Gasserian ganglion (GG) and its third trigeminal division, the internal carotid artery (ICA), the cochlea, the posterior labyrinth, the superior petrosal sinus (SPS), the inferior petrosal sinus (IPS) and the jugular bulb (JB). The middle meningeal artery, on the other hand, could be divided when necessary. We dissected 25 temporal bones preserved in formaldehyde and those of five cadavers in order to define the limits of this approach. Measurements were taken so as to establish the limits of the approach as well as to determine the most appropriate angles and distances in working in this area. As previously suggested by the Senior Author (MS), we found it safer to start working medially in order to identify the IAC and then to extend the dissection laterally. The most constant angle proved to be that between the IAC and the SPS. The distances and areas found appear to be highly variable and difficult to rely upon. A thorough knowledge of this anatomy is of most importance for the surgeon who intends to use this approach.

Brain↗
PubMedDate not supplied

[Localization of preclinical nonpalpable lesions of the breast].

The discovery of mammary neoplastic node in a preclinical stage, most of all not yet palpable, represents the best chance for the surgeon to obtain a real curative exeresis therapy retaining also gland's aesthetics. This kind of situation is more frequent today, because the increased utilization of mammography, ultrasonography and their matched use with the aim to investigate into a population of women with a specific risk. In fact, their sequential use offers the best possibilities of a real earlier diagnosis. In this event the conservative surgical treatment ranks its best curative and aesthetic result. The author's target, based on their own experience, outcomes the comparison between mammography and ultrasonography, pointing out a reliability of the latter similar to the mammography's one upon a specific target at least. The other aspect considered is the possibility of a preoperative localization of the neoplasm using different kind of marks to get the radical tumour exeresis centred on the suspect mass and conservative at its best. The experience suggests more usefulness of metallic marks strung down mammography control, even without using radio-stereotaxic that permits a higher precision but needs adequate facilities with unavoidable more elevated costs. It is finally layed emphasis on the importance of identifying a population at risk to logically utilize, and not indiscriminately, the most modern diagnostic resources.

Adult↗
PubMedDate not supplied

[Fractures of maxillo-facial bones in children. Our experience].

A clinic-statistical study of maxillo-facial fractures in a series of 52 children is reported. This group presents a higher involvement of mandibular body and a low rate M:F than in the literature. Factors responsible for increasing of maxillo-facial traumas in little girls and in school age are analyzed.

Child↗
PubMedDate not supplied

Structural analysis of c-myc in human sporadic colorectal carcinomas.

Analysis of the DNA extracted from the colonic mucosa of 13 patients operated for colorectal carcinoma revealed c-myc rearrangements in three of them. In all cases, the alterations were found both in the histologically normal and in the tumoral mucosa. In one case, a different pattern of rearrangements characterized the two tissues. In all three individuals, the c-myc sequences appeared to be amplified. We suggest that c-myc rearrangements in the histologically normal colonic mucosa of colorectal carcinoma patients could represent a predisposition factor for the development of additional neoplasms.

Adult↗
PubMedDate not supplied

[Esophageal achalasia: its ambulatory treatment by balloon dilatation].

We report immediate and late clinical results achieved in 33 patients with achalasia treated with pneumatic dilation as an outpatient procedure. Thirty patients were seen before any therapy and 3 following a failed esophagomyotomy. All patients were submitted to clinical, radiological and manometric evaluation before treatment: six of them belonged to Adams' class I, 19 to class II and 8 to class III. The dilations were performed with Microvasive Regiflex System (30-35-40. mm.). The average number of dilations per patient was 1.4; one dilation was performed in 25 patients, 2 dilations in 6, and three dilation in two. The patients after the dilation were controlled for a maximum period of 3 hours before being discharged from the outpatient facilities. No complications, worthy of note, was related to the procedures. The clinical results were subdivided in four classes according to Vantrappen's schema. Ten days--immediate results--after the first dilation excellent-good results were obtained in 26 patients (78.8%); moderate results in four (12.1%) and poor results in three (9.1%). The mean LES pressure, evaluated in 15 out of 25 cases fell from 37.6 mmHg. Before treatment to a value of 16.2 mmHg after treatment (p < 0.005). Of the 30 patients followed for an average period of 30.6 months (2-82)--late results--excellent-good results were obtained in 24 (80%), moderate results in 4 (13.3%) and poor in 2 (6.7%). In conclusion the clinical results, of our study, repeat those published in a previous prospective evaluation.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗