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Biomedical subjects

A Rouf

Publications and source records attributed to A Rouf.

2 recordsLinked to original sources

Problem based learning.

PBL, an educational format, stimulates active and life long learning. PBL improves the motivation of students, stimulates integration of disciplines, small group learning; improves clinical reasoning, problem-solving and decision making. It has been introduced increasingly in the curricula of a number of countries in South-East Asia, viz. Thailand, India, Myanmar and Nepal. We feel that the seed of PBL should be sown in the soil of the Undergraduate Medical Curriculum in Bangladesh urgently.

Bangladesh↗

Simultaneous mutations (A/G(-418) and C/T(-384)) in the apo(a) promoter of individuals with low Lp(a) levels.

High plasma levels of Lp(a), a low-density lipoprotein particle with an attached apo(a), are associated with the development of atherosclerosis. We present two simultaneous mutations in the apo(a) promoter (A/G(-418) and C/T(-384)) in healthy Indians with a low Lp(a) level (<5 mg/dl). No such mutations were detected in coronary artery disease positive individuals with very high Lp(a) levels (>200 mg/dl). The mutations described here might be useful in understanding the transcriptional regulation of the apo(a) gene.

Coronary Disease↗