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Biomedical subjects

A Roberts

Publications and source records attributed to A Roberts.

At least 361 records · Page 20Linked to original sources
PubMed1978

Pulsed oxytocin infusion in the induction of labour.

A randomized controlled trial was mounted in which induction of labour at term was successfully accomplished in 12 patients by amniotomy and intermittent (or pulsed) oxytocin, compared with 16 patients receiving continuous oxytocin. In the pulsed group, oxytocin was infused for one minute in every ten using a modified Cardiff Infusion System Mark III in the automatic setting. Compared with the control group the induction-delivery and induction-to-full-dilatation intervals were similar but the total dose of oxytocin required was significantly lower in the pulsed group than in the control group.

Adult↗
PubMed1978

Intermediate alpha1-antitrypsin deficiency and chronic obstructive pulmonary disease in Yugoslavia.

As part of a larger investigation of factors associated with chronic obstructive pulmonary disease among Yugoslavian men, an attempt was made to measure the role played by alpha1-antitrypsin deficiency in the causation of those diseases. Almost 3,000 men from Tuzla, an industrial and mining center in central Bosnia, were screened for alpha1-antitrypsin deficiency. Twenty-six men heterozygous for the Pi MZ phenotype were found in this population. The men with the Pi MZ phenotype were compared with a random sample from the total population. The analysis of the data showed that there is an apparent physiologic impairment associated with Pi Z heterozygosity that produces a shift in the relationships between the different lung volumes without over-all hyperinflation, namely, an increase in residual volume at the expense of vital capacity. However, because of the low prevalence of the Pi Z gene, it does not appear to account for much of the high rate of chronic obstructive pulmonary disease found in this population.

Adult↗
PubMed1977

The blood.

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Biopsy, Needle↗
PubMed1977

Fluids of the eye.

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Aqueous Humor↗
PubMed1977

Synovial fluid.

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Humans↗
PubMed1977

Antitrypsin and chronic obstructive pulmonary disease among Japanese-American men.

A total of 161 patients with chronic obstructive pulmonary disease (COPD) plus 100 control subjects (identified during a study of heart disease in 6,860 Japanese-American men aged 52 to 75 years who were residing in Hawaii) were analyzed for phenotype in search of the antitrypsin gene Z, which has been shown to be associated with pulmonary emphysema in other racial groups. No carriers of the Z gene were found, and the question of whether the rarity or absence of this gene relates to a low frequency of COPD among Japanese-Americans is reviewed.

Chronic Disease↗
PubMed1977

Genetic factors in the development of atheroma and on serum total cholesterol levels in inbred mice and their hybrids.

There is a consistent genetic relationship between the development of atheromata in the aortic sinus wall and serum total cholesterol levels using inbred strains of male mice. This relationship is dependent on a multifactorial (polygenic) type of inheritance that is more complicated than the simple additive-dominance model. There is no special maternal or paternal influence on serum total cholesterol levels or on the development of atheromata.

Animals↗