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Biomedical subjects

A Rizzo

Publications and source records attributed to A Rizzo.

At least 163 records · Page 9Linked to original sources

[Oxygen therapy in pneumology].

Circumstances under which the use of oxygen-therapy in lung disease can be effective and harmless, depend upon a careful evaluation of its indications: they are suggested by the clinical need of correction of hypoxaemia as well as by the awareness of factors determining respiratory failure and of problems concerning O(2) transport and supply to tissues in health and disease. Blood gases monitoring enables to control the effects of treatment on arterial O2 and CO2 tensions thus giving all the useful data for oxygen administering particularly as far as components of hyperoxygenated mixtures, flow rate, duration, use of very effective low-risk devices (Venturi masks) are concerned. Correction of hypoxaemia involves the reduction of hypertension of the pulmonary circulation and hyperglobulia, improvement of tolerance of exertion, and attention to the metabolic compensation of respiratory acidosis. These results are influenced by the nature of the pathogenetic factors behind broncho-obstructive disease, which may lead to either a primarily "bronchitis" or a primarily "emphysematous" syndrome. An interesting feature relates to prognosis in the case of patients making home use of hyperoxygenated mixtures as part of a rehabilitation program, or to improve their quality of life. The cost and benifits of such treatment should be carefully weighed. Lastly, in the event of protracted treatment, attention must be paid to the possibility of toxicity and the means to be adopted for its prevention.

Acidosis, Respiratory↗

[Gas exchange and acid-base equilibrium in chronic bronchitis and in emphysema].

Blood gas data for HbO2% and PaCO2 and determination of acid-base balance enable the biochemical features of bronchial obstruction to be related to primarily "intrinsic" or "extrinsic" factors. Long-term gas studies and ventilation mechanics data (lung elastic recoil pressure, maximum expiratory flow at different volumes and the corresponding recoil pressures) are also of assistance in this respect. Each type of bronchial obstruction thus has its own peculiarities, and these are also reflected in the level of metabolic compensation for respiratory acidosis.

Acid-Base Equilibrium↗

Renal histologic and ultrastructural findings in psychogenic polydipsia and diabetes insipidus.

The renal biopsies of 15 patients affected by polydipsia syndromes were examined under light and electron microscopes. The authors contend that the observed renal lesions (dilatation of the glomerular loops, tubular hypertrophy and vacuolization, and basal membrane swelling) are the morphologic result of tubular hyperfunction in the service of ion reabsorption. This, in turn, is secondary to the increased GFR.

Animals↗