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Biomedical subjects

A Rieger

Publications and source records attributed to A Rieger.

At least 127 records · Page 7Linked to original sources

Effect of preoperative administration of oxytetracycline and neomycin on the development of local tumour recurrences in cases of cancer coli-recti.

In the available literature some evidence has been shown, implying that antibiotic prophylaxis in connection with colorectal surgery might increase the frequency of local recurrences of the carcinoma. 134 patients undergoing elective curative surgery of the large bowel have been followed for 20-52 months. 66 patients had been pretreated with Enterobiotic; 68 patients were controls. In our study, we found no difference between the pretreated and non-pretreated group concerning the frequency of anastomotic suture line recurrences or other types of local recurrences in the operation field.

Adenocarcinoma↗

Spontaneous aortoduodenal fistula. Report of a case.

Spontaneous aortoduodenal fistula is a rare disease. The characteristic clinical picture is a pulsating tumour in the upper abdomen, repeated moderate haemorrhages often combined with severe epigastralgia. The patient very seldom succumbs because of a large first haemorrhage, and there is often time for roentgenologic examinations. The present paper described a case where the diagnosis could not be established until autopsy in spite of angiographic investigation because of clinical suspicion. The only way to treat a patient with any hope of curing him is to perform a grafting of the aorta and suture of the duodenum.

Aged↗

CEA levels at recurrence and metastases; importance for detecting secondary disease.

The relation of CEA plasma levels to prognostic factors was studied in 170 patients with various stages of colo-rectal cancer. Several parameters of known relevance for the prognosis were analyzed. Among the patients with involvement of regional lymph nodes at the time of the primary, 53% had a raised CEA value (greater than 5 ng/ml serum) as opposed to 21% when this was not the case (p less than 0.05%). When serosal break-through had occured, 47% of the patients had raised values compared to 21% of those with no serosal break-through (p less than 0.02%). After radical surgery, all patients who remained healthy acquired persistent low plasma CEA, giving the assay a prognostic value. Altogether 20 patients had local recurrences without distant metastases and were thus potential candidates for a re-operation for cure. 70% had raised CEA plasma values, giving the assay a better than expected usefulness in the clinical follow-up, the significance of the difference from operated and healthy patients or healthy control persons being high, p less than 0.001%. The secondary rise in CEA appeared to be unconnected with whether or not the primary tumor had been accompanied by raised plasma CEA. The localization and the histopathological differentiation of the primary tumor seemed to be of less importance for the serum CEA than the dissemination of the tumor.

Carcinoembryonic Antigen↗