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Biomedical subjects

A Rich

Publications and source records attributed to A Rich.

At least 433 records · Page 24Linked to original sources
PubMed1967

Polyribosomes of growing bacteria.

A method of extracting polyribosomes has been developed which uses lysozyme on bacteria in the exponential phase of growth. This procedure recovers more than 80 percent of the total ribonucleic acid and nearly all of the soluble protein. Analysis of the lysate on sucrose gradients shows that 80 to 90 percent of the ribosomes sediment with the polysome fractions, indicating little or no degradation. The method has been applied to both a Gram-positive and a Gram-negative organism under various growth conditions and has proved uniformly successful.

Centrifugation, Density Gradient↗
PubMed1967

Crystal structure of the 1: 1 complex of 5-fluorouracil and 9-ethylhypoxanthine.

9-Ethylhypoxanthine and 5-fluorouracil form a 1 : 1 crystalline complex. The structure of this complex has been solved by x-ray diffraction analysis. The molecules crystallize in a monoclinic lattice and form a sheet structure in which pairs of fluorouracil molecules are held together by two hydrogen bonds. The 9-ethylhypoxanthine residues fill up the rest of the molecular sheet by forming single hydrogen bonds with each uracil pair.

Chemical Phenomena↗