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Biomedical subjects

A Renzulli

Publications and source records attributed to A Renzulli.

87 records · Page 5Linked to original sources
PubMed1984

Echocardiographic assessment of the subaortic root after implantation of high or low profile mitral prostheses.

In order to evaluate the influence of the profile of mitral prostheses on the outflow tract of the left ventricle, 99 patients underwent M-Mode echocardiography before and after surgery. In 67 cases high profile mitral prostheses had been implanted (48 mechanical and 19 biological); in 32 cases low profile mitral prostheses had been implanted (22 mechanical, 10 biological). Echocardiography showed that the implantation of high profile mitral prostheses did not induce changes of left ventricular diastolic and systolic dimensions ( EDDLV and ESDLV ) while induced significant reduction of left ventricular outflow tract (LVOT) dimension and LVOT/ EDDLV index with subsequent changes in transaortic flow. On the other hand, low profile prostheses did not induce significant changes of left ventricular dimensions, LVOT and LVOT/ EDDLV index. Finally, low profile biological mitral valve prostheses ( Liotta type) induced a significant increase of post-operative dimension of LVOT and LVOT/ EDDLV index. Authors conclude: that the implantation of high profile mitral prostheses changes LVOT dimension and transaortic flow and, that M-Mode echocardiography is a reliable technique to point out these changes.

Adult↗
PubMed1983

A plea for combined cardiac and non-cardiac surgery.

The authors experience with combined cardiac and non-cardiac surgery is reported. Fourty-seven patients underwent contemporary surgical treatment for a cardiac disease and an associated non-cardiac lesion, usually represented by a cholelithiasis, or hernial defects. Two deaths were observed with 4.25% mortality rates. Specific advantages of contemporary cardiac and non cardiac surgery are recorded.

Adult↗
PubMed1981

[Surgical treatment of biliary lithiasis associated with acquired valvulopathy].

Personal experience in the treatment of acquired valvulopathies and biliary calculosis in one operating stage is reported. After examination the risk factors determining onset of bile calculosis in valvulopathic patients, the surgical techniques adopted and the special advantages obtained by associating the two operations at the same session are illustrated.

Adult↗
PubMed1981

[Mesenteric syndrome following the repair of aortic coarctation. Pathogenetic and clinical findings].

Two cases of mesenteric syndrome were observed in 41 patients undergoing correction of aortic coarctation at the School of Heart and Large Vessel Surgery of the 1st Medical Faculty of Naples University. In the light of the latest theories regarding the pathogenesis of the mesenteric syndrome, post-operative arterial hypertension is held to be a decisive factor in the genesis of the complication. Control of pressure is therefore believed to be of considerable importance in the prevention and treatment of the syndrome.

Adolescent↗
PubMedDate not supplied

Gene expression and morphological changes in surgically injured carotids of spontaneously hypertensive rats.

The expression profiles of genes involved in cell proliferation, differentiation and programmed death were investigated in carotids of spontaneously hypertensive rats (SHR) treated with a model of surgical injury that mimics events occurring during arterial grafts, endarterectomy and organ transplantation. The mRNA level of the c-myc, angiotensin II receptor 1 (AT1), Rb/p105, Rb2/p130, Bcl-2 and Bax-alpha genes was assessed by a semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) technique at different times up to 48 h after injury, while the morphological changes were evaluated 30 days after injury. The proliferation marker c-myc increases almost immediately, peaks after 4 h and returns to basal levels after 24 h; the AT1 receptor mRNA reaches its maximal level 48 h after injury. The level of cell cycle exit markers Rb/p105 and Rb2/p130 gradually decreases after injury. The apoptosis marker Bcl-2/Bax-alpha ratio shows a significant reduction only 4 h after injury, resuming the initial value after 24 and 48 h. Morphological analysis reveals that surgical injury in SHR induces adventitial and medial constrictive remodeling changes rather than intima proliferation as in balloon angioplasty. Both molecular and histological data show substantial differences with respect to normotensive rats.

Animals↗