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Biomedical subjects

A Rebora

Publications and source records attributed to A Rebora.

At least 145 records · Page 8Linked to original sources
PubMed1994

Mucin deposits in morphea and systemic scleroderma.

BACKGROUND: Though rarely reported, mucin deposition may be observed in scleroderma. OBJECTIVE: To verify the frequency of significant amounts of mucin in the biopsy specimens. METHODS: Biopsies from 20 patients with scleroderma were reviewed and stained to verify the presence of mucin. RESULTS: Mucin deposits were found in all of the 20 specimens. CONCLUSION: Mucin deposition is probably a constant feature in both morphea and systemic scleroderma. Its relevance in differential diagnosis between scleredema and scleroderma is debatable.

Adolescent↗
PubMed1994

Chronic fatigue syndrome: a novel disorder with cutaneous manifestations.

Persistent and disabling fatigue associated with low-grade fever and other constitutional symptoms, without any known disorder that accounts for it, is recognized as chronic fatigue syndrome (CFS). Skin lesions occur in 10-35% of patients, but their description is inaccurate. Recurrent aphthous stomatitis or persistent Epstein-Barr virus (EBV)-related erythema multiforme have also been reported. Patients may be diagnosed as having CFS only when they fulfill at least 2 major and 8 minor criteria. Major criteria are the presence of debilitating fatigue persisting or recurring for at least 6 months and the absence of any other medical disorder that may explain it. Although different viral or nonviral etiologies have been documented, evidence implicating EBV is gaining support.

Fatigue Syndrome, Chronic↗
PubMed1994

Marginal papular acrokeratodermas: a unified nosography for focal acral hyperkeratosis, acrokeratoelastoidosis and related disorders.

Several entities, quite often similar, share keratotic papules, usually crateriform, along the border of the hands and feet as a common clinical finding. These conditions are acrokeratoelastoidosis of Costa, focal acral hyperkeratosis, acrokeratoelastoidosis of Matthews and Harman, mosaic acral keratosis, hereditary papulotranslucent acrokeratoderma, acrokeratoderma hereditarium punctatum, degenerative collagenous plaques of the hands, keratoelastoidosis marginalis and digital papular calcinosis. We describe two further cases of focal acral hyperkeratosis in two Caucasian women, review the clinical and histological features of the related conditions and suggest that some are variants of the same entity. We propose the simplified concept of marginal papular acrokeratodermas that may be divided into (1) the hereditary type (subdivided into that with and without elastorrhexis) and (2) the acquired type.

Female↗
PubMed1994

Anti-GOR antibodies in lichen planus.

Anti-GOR antibodies characterize patients with autoimmune hepatitis type 2 who are all positive for antibodies to hepatitis C virus (HCV) and have low titers of anti-liver/kidney-microsomal (LKM1) antibody. The documented prevalence of anti-HCV antibodies in patients with lichen planus (LP) and chronic liver disease (CLD) and their negativity for anti-LKM1 antibodies make them eligible for having anti-GOR antibodies. We studied such a possibility in 56 LP patients. Twenty of them had also CLD. Seven CLD patients without LP served as control. Overall, 11/63 patients had anti-GOR antibodies. All of them were anti-HCV positive and had CLD. CLD patients with LP showed the same prevalence of anti-GOR antibodies as CLD patients without LP.

Adult↗
PubMed1994

[Lichen and liver].

Explore the source record for details and available documents.

Hepatitis Antibodies↗
PubMed1993

Keratosis pilaris decalvans non-atrophicans.

A patient is described who presented with an eruption of tiny follicular keratotic papules on the limbs and the trunk accompanied by profuse hair loss. Histologically, a diagnosis of keratosis pilaris was made. The eruption cleared spontaneously in 3 months with complete regrowth of hair. Neither atrophy nor scarring remained. This appears to be the first reported case of keratosis pilaris decalvans non-atrophicans.

Adult↗
PubMed1993

Recurrent impetiginized eczema as a presenting manifestation of cyclic neutropenia.

A patient is described with a persistent, impetiginized dermatitis that worsened periodically, which was preceded by neutropenic episodes during which her circulating neutrophil count fell to 500-600/ml. Each episode lasted 24 h and had a 7-11 day periodicity. The importance of this case depends on the frequency and brevity of the neutrophil trough levels that made the dermatitis appear to be continuous. Similar cases may be more common than expected as isolated abnormal leukocyte counts may be disregarded as laboratory artefacts. Dermatologists should be cautious in managing patients with persistent atypical impetigo.

Adult↗
PubMed1993

Paraneoplastic pemphigoid-pemphigus? Subepidermal bullous disease with pemphigus-like direct immunofluorescence.

BACKGROUND: Paraneoplastic pemphigus is a recently described variant of pemphigus, in which classic immunologic features of pemphigus are associated with subepidermal erythema multiforme-like bullae. CASE REPORTS: Two patients with underlying malignant neoplasm had a bullous disease, which had clinical and histologic features suggestive of bullous pemphigoid while direct immunofluorescence revealed intercellular deposits of IgG and C3 throughout the malpighian layer of epidermis, a pattern usually diagnostic for pemphigus. Indirect immunofluorescence studies were negative. One mg/kg/day prednisone was enough to cure the eruption in a couple of weeks without any recurrence. CONCLUSIONS: The disease differs from the recently reported paraneoplastic pemphigus and from other bullous diseases associating circulating pemphigus-like antibodies with clinical, histologic, and often even immunologic features of bullous pemphigoid.

Aged↗
PubMed1993

Aedes albopictus in Europe: a new challenge for dermatologists.

A patient is reported who was bitten by Aedes albopictus, commonly known as tiger mosquito. The biology of the insect, originally living in the forests of southeastern Asia, and its role in transmitting exotic infectious agents is discussed. Up to this day, only Albania and northern Italy have been colonized, but the biologic characteristics of the insect make its spreading all over Europe highly probable, unless serious attempts to eradicate it are quickly undertaken. Dermatologists should think of the tiger mosquito in the presence of painful, purpuric, large wheals and when patients report a history of multiple attack during daylight.

Aedes↗
PubMed1993

Bullous eruption with circulating pemphigus-like antibodies following interferon-alpha therapy.

Two patients with classic Kaposi sarcoma developed bullous lesions and pemphigus-like 'anti-intercellular-substance' antibodies when treated with interferon-alpha (IFN-alpha). In one of them direct immunofluorescence was consistent with pemphigus/pemphigoid features. The immunoprecipitation test showed no specific bands. The mechanism by which IFN-alpha may induce the production of anti-intercellular-substance antibodies is discussed.

Aged↗
PubMed1993

[Presence of Aedes albopictus in Liguria].

Further data about the presence of Aedes albopictus in the area of Genoa are given with some comments concerning the ecology of this oriental mosquito in the town and the dermatological problems it implies.

Aedes↗
PubMed1993

[Cutaneous mucinosis].

The cutaneous mucinoses are a heterogeneous group of diseases in which mucin accumulates in the skin or within the hair follicle. We divide the cutaneous mucinoses into two groups: the distinctive cutaneous mucinoses in which the mucin deposit is a distinctive histopathologic feature that manifests as a clinically specific lesion, and the diseases associated with histopathologic mucin deposition as an additional finding. This article deals with the clinical and histopathologic features and the treatment of the distinctive cutaneous mucinoses and updates their classification. They may be divided, according to the microscopic location of mucin, into dermal and follicular mucinoses. The former group includes; lichen myxedematosus, acral persistent papular mucinosis, reticular erythematous mucinosis, scleredema, dysthyroidotic mucinoses (i.e. localized myxedema, generalized myxedema, papular mucinoses associated with thyroid diseases), papular and nodular mucinosis associated with lupus erythematosus, self-healing juvenile cutaneous mucinosis, cutaneous mucinosis of the infancy, cutaneous toxic mucinoses (papular mucinosis of the toxic oil syndrome and of eosinophiliamyalgia syndrome), neuropathia mucinosa cutanea, cutaneous focal mucinosis, mucous cyst (digital and of the oral mucosa), while the latter group includes Pinkus' follicular mucinosis and urticaria-like follicular mucinosis.

Adolescent↗