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Biomedical subjects

A Razack

Publications and source records attributed to A Razack.

7 recordsLinked to original sources
PubMed2003

Peritoneal implantation of ureter in a cadaveric kidney transplant recipient.

We report here a case of a kidney transplant recipient in whom the ureter was initially implanted into the peritoneum. Excessive ultrafiltration volume and reversal of serum vs dialysate creatinine ratio when the patient was recommenced on continuous ambulatory peritoneal dialysis first suggested the diagnosis which was subsequently confirmed by a plain abdominal x-ray demonstrating placement of ureteric stent in the peritoneum. This rare complication was successfully corrected with surgical re-implantation of ureter into the bladder and 5 years later, the patient remains well with good graft function.

Adult↗
PubMed1997

A prospective, randomized, double-blind study comparing lignocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy.

OBJECTIVE: To determine the optimum duration for the retention of 2% lignocaine gel intraurethrally as an anaesthetic for flexible cystoscopy in men. PATIENTS AND METHODS: A prospective, randomized, double-blind, placebo-controlled trial was conducted in two parts. Initially, the importance of duration was determined, i.e. whether pain relief was significantly improved when lignocaine gel was instilled for longer than is currently practised. As pain relief was improved by retaining the lignocaine gel for longer, the optimum time was determined in a second trial. Initially, 90 patients were divided into four groups receiving 20 mL of 2% lignocaine gel or plain lubricating gel for 5 or 25 min. Subsequently, 60 men were divided into two groups receiving 20 ml of 2% lignocaine gel for 15 or 25 min. The patients' discomfort was recorded using a 4-point descriptive pain scale and a 100 mm non-graphical visual analogue scale. RESULTS: In the first study, those patients receiving lignocaine gel for 25 min experienced significantly less pain than the other three groups. In the second, lignocaine gel in the urethra for 15 min provided the same level of pain relief as lignocaine for 25 min. CONCLUSION: Pain during flexible cystoscopy can be significantly reduced when 20 mL of 2% lignocaine gel is left in the urethra for 15 min; lignocaine gel would be more effective when left for longer than is currently practised.

Analgesia↗
PubMed1992

Heatstroke: its clinical and pathological presentation, with particular attention to the liver.

Heatstroke is a potentially fatal disorder caused by an extreme elevation of body temperature. It is the most severe of the illnesses produced as a result of a high ambient temperature; however, it also may occur sporadically among individuals working or exercising in more favorable weather conditions, particularly early in their training before acclimatization occurs. The liver is a common site of tissue injury in cases of heatstroke and can be the site of fatal tissue injury in cases that survive the initial neurologic injury. Prompt early recognition of heatstroke as the entity responsible for a given patient's problems and effective early cooling with attention to expected complications can result in complete recovery in most cases. In a minority (< 10%) in whom neurologic injury has not resulted in an early death occurring within the first 2-3 days, the hepatic injury due to heatstroke can result in death that occurs a week or more after the onset of the heat stress, unless the liver is replaced. Recently, two such cases have been referred to the University of Pittsburgh for transplantation. On the basis of these two referrals and a review of the literature, we believe that this problem occurs more often than is currently appreciated, principally because of a lack of knowledge about the problem. In an attempt to correct this information deficit, this review was prepared.

Animals↗