Rifampicin induced shock--a case report.
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Adult↗
Biomedical subjects
A Ramachandran
Publications and source records attributed to A Ramachandran.
Autonomic neuropathy in leprosy.
21 patients of borderline lepromatous and lepromatous leprosy of both sexes were taken for study after exclusion of autonomic disorders. Autonomic functions pertaining to cardiovascular and genital system were carried out. Five healthy volunteers served as controls. Autonomic function tests indicate definite involvement of cardiovascular and genital system. The incidence of autonomic neuropathy in 21 patients studied was ranging from 14.3 to 57% for various tests. There is involvement of parasympathetic system (vagus nerve) which occurred early and more common than sympathetic. The sympathetic damage is always associated with parasympathetic damage. The severity of autonomic neuropathy is found to be high in leprosy of longer duration. Autonomic neuropathy widely occurs in leprosy as in diabetes mellitus.
Adult↗
Autonomic neuropathy in leprosy.
21 patients of borderline lepromatous and lepromatous leprosy of both sexes were taken for study after exclusion of autonomic disorders. Autonomic functions pertaining to cardiovascular and genital system were carried out. Five healthy volunteers served as controls. Autonomic function tests indicate definite involvement of cardiovascular and genital system. The incidence of autonomic neuropathy in 21 patients studied was ranging from 14.3 to 57% for various tests. There is involvement of parasympathetic system (vagus nerve) which occurred early and more common than sympathetic. The sympathetic damage is always associated with parasympathetic damage. The severity of automatic neuropathy is found to be high in leprosy of longer duration. Autonomic neuropathy widely occurs in leprosy as in diabetes mellitus.
Adult↗
Multiple relapses in borderline leprosy--a case report.
A case of borderline lepromatous leprosy with a history of 5 years duration of disease, was first seen in 1971 and treated with graded doses of dapsone in the OP Clinic of the Institute. He became inactive and bacteriologically negative in 3 years. While continuing on dapsone therapy he relapsed into active dapsone resistant leprosy 3 1/2 years later. He was admitted in the hospital and given Rifampicin 600 mg. daily for 15 days along with dapsone 100 mg. daily. He again became inactive and bacteriologically negative within 3 years. 3 years later under regular dapsone therapy he relapsed again for the second time into active BT leprosy, but remained bacteriologically negative. He was given 3 drug regimen subsequently and became clinically inactive within 15 months.
Adolescent↗
Increased LDL cholesterol in non-insulin-dependent diabetics with maculopathy.
Serum cholesterol and its various lipoprotein fractions and triglycerides were measured in 50 non-insulin-dependent diabetic patients, 25 without retinopathy (group A) and 25 with diabetic maculopathy (group B) initially before control of diabetes, and again, after achieving good metabolic control. The lipid parameters were also estimated in 25 healthy non-diabetic subjects. The groups were well matched for sex, age, duration of diabetes and body weight. Mean serum total cholesterol and LDL cholesterol levels were significantly higher in group B when compared to group A, before and after achieving good metabolic control of diabetes (p less than 0.001). Mean total/HDL cholesterol and mean LDL/HDL cholesterol ratios were also significantly increased in group B as compared to group A (p less than 0.01) both before and after good diabetic control in these patients. Mean serum HDL and VLDL cholesterol and triglyceride concentrations were similar in groups A and B. The mean serum lipid concentrations in the diabetic patients without retinopathy (group A) were comparable to those of non-diabetic subjects.
Adult↗