Search PubMed⌕ Search

Biomedical subjects

A R Temple

Publications and source records attributed to A R Temple.

50 records · Page 3Linked to original sources

Fenfluramine poisoning.

Fenfluramine is a substituted phenylethylamine structurally related to amphetamine. Within three hours following the ingestion of 1,600 mg of fenfluramine, a 17-year-old girl, who was initially agitated and had tachycardia, developed convulsions, cardiac arrhythmia, and cardiorespiratory arrest. In previously reported cases, flushing, sweating, mydriasis, tachycardia, and agitation commonly occur, as well as convulsions and abrupt cardiorespiratory arrest. The rapid onset and progression of symptoms, the short interval between ingestion and death, and the lack of responsiveness to resuscitative measures are common findings in fatal cases.

Adolescent↗

Taste as a deterrent in pediatric poisonings.

Seven hundred and two children were tested to see how much they would ingest of two commercially available potassium supplements, one an effervescent tablet and the other a powder. The results showed that the children would not ingest either formulation in amounts that even equalled a single adult therapeutic dose. The children appeared to be deterred by both the effervescent quality of the tablet and the unpleasant, metallic after-taste of the powder. An unpleasant taste may act as a deterrent to the child, keeping him from ingesting a toxic amount of a product, at least, when the product has relatively low toxicity.

Child, Preschool↗

Recent advances in diagnosis and management of croup.

Croup is a syndrome of inspiratory stridor, cough, and hoarseness, due to varying degrees of laryngeal obstruction. It is a viral disease and must be differentiated from epiglottitis. In addition to a careful clinical assessment, neck films are the most valuable diagnostic tool in differentiating these two. The principle modes of therapy for croup include provision of adequate hydration, ensuring maximum available humidification, sedation, and administration of intermittent positive pressure breathing (IPPB) with nebulized racemic epinephrine. The latter mode of therapy will provide symptomatic relief and may eliminate the need for hospitalization and tracheostomy. Steroids offer little benefit in treating this disease, and antibiotics offer none.

Child↗