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Biomedical subjects

A R Solomon

Publications and source records attributed to A R Solomon.

85 records · Page 5Linked to original sources
PubMed1983

Subcutaneous alternariosis.

Alternaria species are common plant pathogens, but a rare cause of human infection. Previously reported cases of cutaneous alternariosis (Alternaria alternata) in both healthy and immunosuppressed hosts have been characterized by a chronic localized ulcerative eruption in exposed sites. Dermal granulomatous infiltration and variable epidermal changes, with hyphae in both the dermis and epidermis, are characteristic. We present a case with certain unique features. This is the first reported human infection with Alternaria dianthicola. In addition, our patient showed the unusual presentation of clinically noninflammatory subcutaneous nodules of the chest wall. The subcutaneous location of the granulomatous process may have been attributable to deep traumatic inoculation. The circumscribed nodular quality of the infection allowed a surgical therapeutic approach.

Alternaria↗
PubMed1983

Treatment site reactions to Zyderm Collagen Implantation.

Two cases of treatment site granulomatous reaction to Zyderm Collagen Implant that occurred in spite of a negative skin test are reported. A delayed hypersensitivity reaction to ZCI is suggested by the clinical time course and the histologic findings of hypersensitivity granulomas. Humoral immunity is also implicated in the reaction since elevated anti-Zyderm serum antibodies and plasma cell infiltrates are present. Resolution of the clinical signs and symptoms occurred over several months with no treatment. The physician using ZCI should be aware of this rare adverse reaction.

Acne Vulgaris↗
PubMed1983

Pigmented purpuric lichenoid dermatitis of Gougerot-Blum mimicking Kaposi's sarcoma.

A case of pigmented purpuric lichenoid dermatitis of Gougerot-Blum is presented and the pertinent literature is reviewed. This case is unusual in that the lesions were unilateral and very limited in extent. The patient presented with a localized pigmented purpuric eruption of plaques on the dorsum of one foot which mimicked Kaposi's sarcoma. However, a biopsy confirmed the diagnosis of pigmented purpuric lichenoid dermatitis of Gougerot-Blum.

Adult↗
PubMed1981

Serous extravasation granuloma. A parotid mass.

A new benign lesion of the parotid gland, the serous extravasation granuloma, occurred as a unilateral, painless parotid mass. Histologically, the mass was outlined by a fibrous capsule within which there was granulation tissue that was admixed with histiocytes and giant cells of a foreign-body type with abundant PAS-positive granules in their cytoplasm. Atrophic duct spaces and microsialoliths occurred within the lesion. Trauma to the parotid gland was the proposed origin.

Aged↗
PubMed1981

A controlled comparison of amcinonide cream 0.1 percent and halcinonide cream 0.1 percent in the treatment of eczematous dermatitis.

A 2-week, double-blind clinical trial was conducted to compare the efficacy and cosmetic acceptability of amcinonide cream 0.1 percent and halcinonide cream 0.1 percent in the treatment of 29 patients with eczematous dermatitis. The dermatologic status of each patient was rated by improvement in clinical signs and symptoms, by the investigator's overall evaluation, and by two patient evaluations. Both medications produced statistically significant and equivalent improvement by Week 2. However, amcinonide was significantly favored in the efficacy evaluation of relief from burning pain at Week 2 and in patient acceptability evaluations in regard to the absence of burning, stinging, and itching on application. The role of propylene glycol in the formulation of the halcinonide cream as a contributing cause of irritation is noted.

Adolescent↗
PubMed1978

The value of the amylase/creatinine clearance ratio in the diagnosis of acute pancreatitis.

Acute pancreatitis usually confronts the clinician with a difficult diagnostic task. For years, the primary laboratory diagnostic tests were the serum and urine amylase and the serum lipase determinations. Recent studies have introduced the concept of the amylase/creatinine clearance ratio as a means of increasing the specificity of the laboratory diagnosis. This paper reviews the laboratory evaluation of acute pancreatitis with emphasis on the rationale, derivation, and specificity of the amylase/creatinine clearance ratio.

Acute Disease↗
PubMedDate not supplied

The pathology of head and neck tumors: squamous and mucous-gland carcinomas of the nasal cavity, paranasal sinuses, and larynx, part 6.

Carcinomas of the nasal cavity and paranasal sinuses are statistically dominated by squamous-cell lesions, which account for between 85% and 90% of the epithelial malignancies in these sites. Neoplasms of glandular derivation are far less frequent, accounting for between 4% and 8% of carcinomas in this region. Both classes of malignancy, however, indicate an ominous prognosis for their hosts, and for both, it is the extent of the cancer, and hence the clinical stage, that is the major determinant. The clinicopathologic characteristics of squamous-cell and glandular carcinomas of the nasal cavity and paranasal sinuses are presented, and for the latter, a review of their presentation in the larynx is also offered.

Adenocarcinoma↗
PubMedDate not supplied

The pathology of head and neck tumors: neoplasms of cartilage, bone, and the notochord, part 7.

Neoplasms of the supporting tissues in the head and neck are outnumbered by their histologic counterparts in the trunk and extremities. This is especially true for tumors of bone, cartilage, and the remnants of the notochord. Malignancies occurring in all three tissues, however, are just as lethal as those sited elsewhere. Chondrosarcomas and osteogenic sarcomas of the facial bones are resistant to all conventional modes of therapy, manifest many recurrences, and have an often protracted morbidity. The craniocervical chordoma manifests a similar biologic course. For the tumors of cartilaginous origin and the osteogenic sarcomas, the initial surgical attempt at removal is of key importance. Neoplasms present at the margins of resection have a poor prognosis. Chorodomas are not likely to be cured by any modality.

Bone Neoplasms↗
PubMedDate not supplied

The pathology of head and neck tumors: carcinoma of the nasopharynx, Part 11.

The past decade has witnessed extraordinary advances in the epidemiology, virology, and immunology of carcinomas of the nasopharynx. There has not been a parallel growth in the study of morphologic expressions of the neoplasms. In great part, this has been due to a lack of a universally accepted histologic classification. As a consequence, correlation between histology and other factors relating to the pathogenesis of these neoplasms has been impeded. The World Health Organization (WHO) has proposed a histologic classification of nasopharyngeal carcinomas as squamous-cell, nonkeratinizing, and undifferentiated. This report presents and argument in favor of using the WHO classification and a hypothesis relating to the histogenesis of the 3 types of nasopharyngeal carcinoma.

Adolescent↗
PubMedDate not supplied

The pathology of head and neck tumors: mucosal melanomas, part 13.

Pigmented lesions, including melanomas, of the mucous membranes of the head and neck are far outnumbered by their counterparts in the skin. This relative dearth is partially responsible for the fact that scientific inquiry into mucosal melanomas has not kept pace with the advances in knowledge of the pathogenesis of cutaneous melanomas and their diagnosis and treatment. Integral to these latter advances have been the refinements in clinical and histologic classification and clinicopathologic correlations with quantitative evaluation of melanomas of skin-enhancements that up to now have been singularly lacking for mucosal melanomas. This report acknowledges this slowness in progress, present recommendations for purifying the nomenclature of pigmented lesions of the mucosae, and at the same time, also notes the poorer prognosis for melanomas of the upper aerodigestive tracts, as a group, when compared with cutaneous melanomas. Only prospective studies will answer the question of whether the poor prognosis is intrinsic to these mucosal melanomas or whether delay in detection and removal are responsible.

Dental Amalgam↗