Biomedical subjects

A R Hansen

Publications and source records attributed to A R Hansen.

38 records · Page 3Linked to original sources

PubMedDate not supplied

Sonographically detected subarachnoid hemorrhage: an independent predictor of neonatal posthemorrhagic hydrocephalus?

Blood from an intraventricular hemorrhage (IVH) can collect in the basilar cisterns and cause ventriculomegaly and eventual need for ventriculoperitoneal (VP) shunt. We looked for sonographic evidence of subarachnoid hemorrhage (SAH) in three basal cisterns and in the Sylvian fissure of 82 infants with IVH, 30 of whom had ventriculomegaly. We found that ultrasonographically diagnosed SAH and measurement of ventricular blood volume predict ventriculomegaly and need for VP shunt.

Cerebral Ventricles↗

PubMedDate not supplied

Disposition of radiolabeled flumequine in rat and dog.

Single doses of 14C-flumequine (a urinary tract antibacterial) were given to rats and dogs. Unchanged drug accounted for more than 80% of the drug in plasma of rats but only 25-50% in plasma of dogs. Although only a small percentage of the dose was excreted in the urine of each species as unchanged drug, a wide differentiation in the urinary metabolite profiles was observed. No significant tissue retention was seen in rats or dogs.

Animals↗