Search PubMed⌕ Search

Biomedical subjects

A R Gold

Publications and source records attributed to A R Gold.

8 recordsLinked to original sources
PubMed1991

Effect of weight loss on upper airway collapsibility in obstructive sleep apnea.

Previous investigators have demonstrated in patients with obstructive sleep apnea that weight reduction results in a decrease in apnea severity. Although the mechanism for this decrease is not clear, we hypothesize that decreases in upper airway collapsibility account for decreases in apnea severity with weight loss. To determine whether weight loss causes decreases in collapsibility, we measured the upper airway critical pressure (Pcrit) before and after a 17.4 +/- 3.4% (mean +/- SD) reduction in body mass index in 13 patients with obstructive sleep apnea. Thirteen weight-stable control subjects matched for age, body mass index, gender (all men), and non-REM disordered breathing rate (DBR) also were studied before and after usual care intervention. During non-REM sleep, maximal inspiratory airflow was measured by varying the level of nasal pressure and Pcrit was determined by the level of nasal pressure below which maximal inspiratory airflow ceased. In the weight loss group, a significant decrease in DBR from 83.3 +/- 31.0 to 32.5 +/- 35.9 episodes/h and in Pcrit from 3.1 +/- 4.2 to -2.4 +/- 4.4 cm H2O (p less than 0.00001) was demonstrated. Moreover, decreases in Pcrit were associated with nearly complete elimination of apnea in each patient whose Pcrit fell below -4 cm H2O. In contrast, no significant change in DBR and a minimal reduction in Pcrit from 5.2 +/- 2.3 to 4.2 +/- 1.8 cm H2O (p = 0.031) was observed in the "usual care" group. We conclude that (1) weight loss is associated with decreases in upper airway collapsibility in obstructive sleep apnea, and that (2) the resolution of sleep apnea depends on the absolute level to which Pcrit falls.

Adult↗
PubMed1991

Premises liability.

Like other health care providers, optometrists have a duty to maintain offices and equipment in a safe condition. Failure to meet this duty results in premises liability. This article discusses premises liability with particular emphasis on pupillary dilation as a causative factor for patient injuries.

Humans↗
PubMed1978

Rise in female-initiated sexual activity at ovulation and its suppression by oral contraceptives.

This study was designed to test the hypothesis that women exhibit peaks of sexual activity at ovulation, as would be predicted from estrous effects in animals. Married women who used contraceptive devices other than oral contraceptives experienced a significant increase in their sexual behavior at the time of ovulation. This peak was statistically significant for all female-initiated behavior, including both autosexual and female-initiated heterosexual behavior, but was not present for male-initiated behavior except under certain conditions of contraceptive use. Previous failures to find an ovulatory peak may be due to use of measures of sexual behavior that are primarily determined by initiation of the male partner. Women using oral contraceptives did not show a rise in female-initiated sexual activity at the corresponding time in their menstrual cycles, probably owing to the suppression of ovulatory increases in hormone secretion by the oral contraceptives.

Adult↗
PubMed1978

Reexamining barriers to women's career development.

This paper reviews recent literature concerned with beliefs and values relevant to women's careers. Changes in sex-role stereotyping, potential problems relating to affirmative action programs, and the conflict between "counter-culture" values and values of the women's liberation movement are discussed.

Achievement↗
PubMed1975

Cognitive and hormonal factors accecting coital frequency.

Sexual behavior of female undergraduates was assessed by daily questionnaries. Of the 24 subjects, 13 were taking oral contraceptives ("pill" subjects) and 11 were using other methods of birth control ("nonpill" subjects), primarily diaphragm or male prophylactic methods. Three main results were obtained: (1) Intercourse rates were lowest during menstruation and highest immediately following menstruation. (2) Self-rated sexual arousal on a given day correlated with the type of heterosexual encouters on that day rather than with period of the menstrual cycle. (3) Pill subjects reported intercourse on more days than nonpill subjects but reported a lower number of intercourse sessions on day with intercourse than nonpill subjects. These results are interpreted within a general framework of sexual behavior which recognizes the sexual behavior of humans as primarily influenced by cultural and cognitive factors. The possibility is discussed that female sexual behavior might also be found to be affected by hormones if more sensitive measures were used.

Adolescent↗