Biomedical subjects
A R Colón
Publications and source records attributed to A R Colón.
Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.
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Intestinal lymphonodular hyperplasia of childhood: patterns of presentation.
In this retrospective analysis we searched for a constellation of signs or symptoms attributable to childhood lymphonodular hyperplasia (LNH). Of 147 children with documented LNH reviewed, 43% had lesions in the small bowel, and 57% in the large bowel. Children in this study presented with complaints of abdominal pain (58%) and bright red blood per rectum (32%). Physical examination revealed little except right lower quadrant (RLQ) abdominal tenderness and "fullness" in 35%. The pain was periumbilical, dull-cramping, rarely acute, and nonradiating. The hematochezia was most commonly streaky red in mucoid strands adhering to the stools, with no associated tenesmus. Three clinical patterns emerged: (a) Under 1 year of age most patients were male, with painless bleeding and pancolonic LNH. (b) Between 2 and 6 years, although the LNH was predominantly colonic, pain and bleeding occurred equally. (c) From 7 years old on, the main symptom was abdominal pain, but LNH distribution was nearly equal between the small bowel and the colon. To date, our long-term follow-up of the children with isolated LNH has revealed no sequelae.
Recurrent cough of 3 years duration.
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Eosinophilic gastroenteritis.
A 4-month-old boy presented with signs of intermittent pyloric obstruction. Peripheral eosinophilia, along with radiographs showing antral-pyloric and duodenal narrowing, suggested the diagnosis of eosinophilic gastroenteritis. A brief discussion of the disease process follows.
Childhood pancreatitis with biliary calcareous disease.
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Systemic lupus erythematosus in children: the complex problems of diagnosis and treatment encountered in 101 such patients at the Mayo Clinic.
Between 1945 and 1970, 101 children (86 girls and 15 boys) with systemic lupus erythematosus were evaluated at the Mayo Clinic. Only 9 children were less than 9 years old at the time of diagnosis. The most frequent presenting complaint was arthralgia; fever, fatigue, and a "butterfly" malar rash also were common. Renal involvement, found in more than 76 per cent of patients, was a prognostically poor sign. The overall survival of children with renal involvement is improved by the use of adequate steroid therapy.
Defecation patterns in American infants and children.
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Presently recognized forms of inherited jaundice in infancy. A summary and review.
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Hepatic encephalopathy treated with L-dopa, recovery followed for 18 months.
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Childhood pulmonary alveolar proteinosis (PAP). Report of a case and review of the literature.
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