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Biomedical subjects

A R Chang

Publications and source records attributed to A R Chang.

47 records · Page 3Linked to original sources

An analysis of the pathology of 3003 appendices.

An analysis was made of 3003 appendices seen in a ten-year period (1969-1978) in the Dunedin Hospital Surgical Pathology Laboratory. Acute appendicitis was found to be a disease of the young, with 1385 (80%) cases out of 1711 occurring in patients less than 30 years of age. Faecaliths and lymphoid hyperplasia were found only in a very small percentage of acute appendicitis cases, and this lends further support to the hypothesis that acute appendicitis is a disease of western culture where the diet is low in cellulose. There was no seasonal predilection for acute appendicitis. Other pathological conditions were discussed and illustrated. More normal appendices and more of those exhibiting non-acute conditions were removed from females. The submission of appendices for histological evaluation is a most worthwhile procedure, with a significant yield of unexpected important information.

Acute Disease↗

Test and teach. Number twenty-one. Diagnosis: practolol induced sclerosing peritonitis.

A relatively uncommon but unique and life threatening iatrogenic condition is described. There are few aids to diagnosis but once it is known that the patient has been on practolol the surgical and pathological findings are pathognomonic. Other practolol related side effects are usually present in the patient. The conditions may develop months or possibly years after cessation of intake of the drug and further cases may occur, although practolol has been withdrawn from use. Awareness of the condition is therefore of continuing importance.

Angina Pectoris↗