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Biomedical subjects

A Puras

Publications and source records attributed to A Puras.

54 records · Page 3Linked to original sources

[Endobronchial tuberculosis].

Eight hospitalized patients with endobronchial tuberculosis are reported. Diagnosis was reached in six patients by the demonstration of acid-alcohol resistant bacilli in the bronchial aspirate. In the fifth patient microscopic examination of the bacteria in the liquid obtained by aspiration of a paraspinal abscess was positive. In the last patient diagnosis was established by the positive growth in Lowenstein's medium of lymph node extracts. The clinical, radiologic, endoscopic and microbiologic features are discussed.

Adolescent↗

[Peritoneal hydatidosis with fistulization into the sigmoid colon].

A case is presented of peritoneal hydatidosis with fistulization into the sigmoid in a patient who had previously undergone surgery for hepatic hydatidosis. The clinical picture made its debut as an alteration in intestinal habit followed by the appearance of diarrheic syndrome and expulsion of hydatid membranes. The natural history of peritoneal hydatidosis, its complications and therapeutic guidelines are discussed.

Aged↗

[Clinical characteristics of arterial hypertension in the elderly].

The clinical characteristics of systolic and diastolic hypertension in 75 and of systolic hypertension in 50 elderly patients have been studied and the results have been compared to those obtained in 23 normotense elderly controls and 500 young patients with essential hypertension. A greater incidence in cardiovascular and neurologic morbility was observed in the hypertense elderly, existing also a greater incidence of electrocardiographic abnormalities and impairment in renal function. The changes in blood pressure with postural changes and isometric and physical exercise were evaluated in a subgroup of these patients, finding that the elderly with hypertension, specially those with systolic hypertension, showed orthostatic hypotension, and an increase in blood pressure with exercise, reaching levels that could potentially cause the clinical complications.

Aged↗

[Idiopathic varicocele in children].

The authors present their experience with ten children operated on for left-sided idiopathic varicocele over a period of seven years. The treatment was high ligature of the spermatic vein with a favorable outcome in all cases. The histology of the testes, seen in biopsy, demonstrated a variable degree of damage. For this reason the authors recommend that this operation should be done in childhood in order to avoid problems of subfertility or infertility in adult life.

Adolescent↗

[Value of the expression of p21RAS, P53, Bcl-2 oncoproteins and Ki-67(MIB-1) antigen of cellular proliferation in the diagnosis and prognosis of thyroi].

INTRODUCTION: The thyroid gland is a good organ for the study of genetic alterations in tumoural development and progress. The study of oncogenes and antigens of cellular proliferation is of interest. MATERIAL AND METHODS: 36 cases of thyroid adenomas, 58 papillary carcinomas, 32 follicular carcinomas, 2 anaplastic carcinomas and 12 medullary carcinomas were selected. Clinical and histological prognostic factors were studied and an immunohistochemical study with Ki-67 (MIB-1), p53, Bcl-2 and p21 RAS antibodies was performed. RESULTS: The proliferative rate Ki-67 (MIB-1) showed statistical differences in adenomas and follicular carcinomas. The p53 protein did not appear in adenomas, but was shown in those carcinomas with bigger histological dedifferentiation. A relationship was also established with greater age, larger size and progression of the tumour. The Bcl-2 protein was high in the normal thyroid, in the adenomas and in the carcinomas, decreasing in correlation with histological dedifferentiation, and totally disappearing in the anaplastic carcinomas. In medullary carcinomas its disappearance was correlated with mortality. The intense expression of the p21 RAS protein in papillary carcinomas is statistically correlated with advanced clinical studies. CONCLUSIONS: The differences in the proliferative rate between adenomas and follicular carcinomas can be of help in differential diagnosis. The p53 manifestation and the loss of the Bcl-2 expression are correlated with the histological redifferentiation process. An intense manifestation of p21 RAS in papillary carcinoma is correlated with tumoural progression.

English Abstract↗