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Biomedical subjects

A Puech

Publications and source records attributed to A Puech.

At least 73 records · Page 4Linked to original sources

[Biochemical and pharmacological approach to the functional disorders observed in demyelination mutants (GABAergic and noradrenergic systems)].

The abnormal behavior observed in diseases of myelin remains unexplained. Mutations in the mouse in which the main phenotypic expression involves myelination is a useful tool. As tonic seizures are observed, an electrophysiological, pharmacological and biochemical study was performed. The convulsions seem to be linked mainly to an alteration of the alpha-adrenergic system. The GABA-ergic system is also modified. The relations between these observations and the defect of myelination remain to be elucidated.

Animals↗

[Structure-mobility relationships in thin-layer chromatography. Applications to some progestogens (author's transl)].

A study has been made on the quantitative relationship between the chromatographic mobility and the structure of progestogenic steroids. The coefficient K, corresponding to the fundamental skeleton, and the parameters of different substituents were calculated from the RM values. The results obtained with eighteen steroids tested in two solvent systems of low dielectric constant and low polarity have been improved satisfactorily.

Chemical Phenomena↗

[Not Available].

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History, Early Modern 1451-1600↗