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Biomedical subjects

A Prior

Publications and source records attributed to A Prior.

48 records · Page 3Linked to original sources
PubMed1986

What determines whether an elderly patient can use a metered dose inhaler correctly?

The metered dose inhaler (MDI) technique of 30 elderly patients (mean age 79.9 years) was assessed. Sixty per cent were competent, though only 10% had an ideal technique; 40% were incompetent. Inadequate timing of actuation and inhalation was the most frequent error made. Competence was significantly related to mental status questionnaire (MSQ) scores of 7/10 or more. Patients who were first prescribed an MDI in hospital were significantly more likely to be competent than those prescribed an MDI by the general practitioner. Competence was not related to age, underlying diagnosis or duration of MDI therapy. Elderly patients requiring MDI therapy should be carefully selected and properly instructed by the prescribing doctor.

Aerosols↗
PubMed1986

Cardiogenic shock without a critically raised left ventricular end diastolic pressure: management and outcome in eighteen patients.

Eighteen patients in whom shock developed after acute myocardial infarction are described. There was electrocardiographic evidence of acute inferior infarction in 11, of inferolateral infarction in three, and of anteroseptal infarction in four. In all cases the right atrial pressure was the same as or exceeded the end expiratory pulmonary artery wedge pressure. Plasma volume expansion of 100-2500 ml was needed to produce an optimum pulmonary artery wedge pressure. Eleven patients needed additional inotropic support with dopamine. Despite the absence of a critical increase in pulmonary artery wedge pressure, potential or actual hypoxia was almost always present. Six patients needed endotracheal intubation and mechanical ventilation because they had severe hypoxia that was unresponsive to supplemental inspired oxygen. Life threatening arrhythmias were also common (ventricular fibrillation in seven patients and complete heart block in four). Five patients died. All surviving patients are well and only one requires treatment for heart failure.

Aged↗
PubMed1986

Management of irritable bowel syndrome.

Few drugs are of proven efficacy in irritable bowel syndrome. Bulking agents probably relieve constipation, spasmolytics may alleviate pain and antidiarrhoeals help control urgency and diarrhoea. With a combination of reassurance and therapeutic intervention up to 75% of patients can be expected to improve. For the 25% who do not, alternative therapies such as stress management, psychotherapy or hypnotherapy may prove effective.

Antidepressive Agents↗
PubMed1986

Irritable bowel syndrome. Definitions and epidemiology.

Irritable bowel syndrome affects up to 20% of the population, is more common in females and is one of the commonest disorders dealt with by gastroenterologists. It is now recognised that the disorder is not confined to the colon and can give rise to a wide variety of different symptoms.

Colonic Diseases, Functional↗
PubMed1986

Familial Barrett's oesophagus?

Two sisters presenting with Barrett's oesophagus both at the age of 66, are described. The endoscopic appearances revealed striking similarities in terms of severity and extent of the lesion and the presence of a hiatus hernia. At oesophageal manometry low lower oesophageal sphincter pressures were recorded in each case. These observations raise the possibility that familial factors may influence the development of this condition, and likely mechanisms are discussed.

Aged↗
PubMed1984

Controlled trial of hypnotherapy in the treatment of severe refractory irritable-bowel syndrome.

30 patients with severe refractory irritable-bowel syndrome were randomly allocated to treatment with either hypnotherapy or psychotherapy and placebo. The psychotherapy patients showed a small but significant improvement in abdominal pain, abdominal distension, and general well-being but not in bowel habit. The hypnotherapy patients showed a dramatic improvement in all features, the difference between the two groups being highly significant. In the hypnotherapy group no relapses were recorded during the 3-month follow-up period, and no substitution symptoms were observed.

Acute Disease↗
PubMed1980

Evidence of infection by viruses in small British field rodents.

Four populations of small wild British rodents were studied by capture--re-capture methods over a period of three years. Samples of blood were taken from these animals and tested for antibodies to nine viruses. Animals were removed from another 11 sites around the UK, and immunosuppressed. Samples of tissue from these animals were tested for the presence of viruses by passage in laboratory mice and serum samples from some of them were tested for antibody to the nine viruses. Indications were found of the possible influence of epizootic outbreaks of certain diseases on animal populations.

Adrenocorticotropic Hormone↗
PubMed1980

A note on some Enterobacteriaceae from the faeces of small wild British mammals.

Over a four-year period 878 samples of faeces were collected from five species of small wild rodents and two species of shrews at sites in England, Scotland and Wales. A search was made for Salmonella in these samples but no isolations of this genus were made. Several other genera of Enterobacteriaceae were identified.

Animals↗
PubMed1977

The anion gap.

Explore the source record for details and available documents.

Aged↗
PubMedDate not supplied

A self-regulating device for continuous reinfusion of jejunostomy effluent.

The management of a patient with an enteric fistula producing a large volume of effluent is time-consuming and complicated. In patients requiring defunctioning procedures the eventual aim is restoration of intestinal continuity. Prior to surgery however it is prudent to ensure that the bowel distal to the stoma will cope with the sudden return to its normal role without diarrhoea or colic. This paper describes a simple, cheap, portable device which can be easily made. The device is closed, self-regulating and can be adjusted to patients' requirements.

Equipment Design↗