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Biomedical subjects

A Pollak

Publications and source records attributed to A Pollak.

At least 235 records · Page 13Linked to original sources

[Congenital hepatic fibrosis and polycystic disease of the kidneys in two siblings (author's transl)].

Report of 2 siblings, aged 12 1/2 and 9 years, with congenital hepatic fibrosis and polycystic disease of the kidneys. Hepatosplenomegaly had been noted in both children at birth. The younger child had suffered from oliguria aged 2 1/2 years. At diagnosis both children had low platelet counts, one also had leucopenia. The cystic disease of the kidneys was verified by angiography. Coeliacography and splenopartography were diagnostically irrelevant. The diagnosis only became apparent from liver biopsy which was performed during splenectomy. After splenectomy there was an increase of platelets, white blood cells and the clotting factors II, V and X. The three years follow-up showed a constancy of renal impairment and of the minor oesophageal varices observed in the one patient who did not have a spontaneous spleno-renal anastomosis. So far no bleeding has been observed. Porto caval anastomosis was omitted in both children. Pros and cons are being discussed.

Child↗

[Calcification of the urinary bladder, a rare finding in the newborn (author's transl)].

The rare X-ray finding of urinary bladder wall calcifications in a newborn is reported. The newborn suffered from micturition disturbance caused by urethral valves, bilateral hydroureter and bilateral hydronephrosis. No possible definite cause for the calcification of the bladder wall could be found. The calcifications could never be detected by X-ray after the age of 5 months.

Calcinosis↗

[Carbohydrate metabolism of infants with prenatal dystrophy and infants of diabetic mothers. Glucosetolerance and insulinsecretion in the first week of life (author's transl)].

Alterations of carbohydrate metabolism were studied in infants of insulin dependent diabetic mothers and in small for date babies with and without prenatal dystrophy. Glucose assimilation (Kt-value) and insulin secretion after i. v. glucose load were examinated on the 1st, 3rd, and 5th day of life. Infants of diabetic mothers showed the highest Kt-values, fasting insulin levels and insulin peaks of all patients examinated. Hyperinsulinism and Kt-values decreased from the 1st to the 3rd day and from the 3rd to the 5th day. In this group the infants of mothers with strictly controlled diabetes showed lower Kt-values, lower insulin peaks and less pronounced cushingoid facies. Small for date babies, on the other hand, had a reduced glucose tolerance on the first day, which normalised up to the 3rd day. The glucose tolerance in small for date babies with prenatal dystrophy, however, showed a tendency to deteriorate again from the 3rd to the 5th day with decreasing Kt-values as well as reduced insulin secretion, which was well documented in two cases. Deterioration of pancreas function and failing adaption to post partum nutrition is put forward as a tentative explanation.

Blood Glucose↗

[The umbilical cord blood lead concentration: a comparison between an urban and rural population (author's transl)].

The cord blood lead level was determined to 40 newborn infants. The values were significantly higher in the infants born to mothers resident in Vienna than in the infants born to the group of mothers from the rural surroundings of Eisenstadt. The overall mean blood level was 17.7+/-7.4 mug/100 g. Increasing pollution requires investigations concerning possible effects on the growing fetus and would serve as foundation for future trend assessment studies.

Air Pollution↗

Prospective and retrospective examination of an easily applicable score to predict the probability of premature birth defined by weight.

An easily applicable score to predict the risk of prematurity (Tab. I) (defined by weight) is examined prospectively (scoring during 6 th month of pregnancy) in 431 and retrospectively (obtained after delivery) in 1183 pregnancies. In the prospective study (Tab. II) 71.4% of all pregnancies resulting in babies below 2501 g exceed the proposed 50 points risk probabilty limit whereas only 18.7% of pregnancies with babies of more than 3000 g do so. Excluding pregnancies with 20 or more risk points and excellent prenatal care (8 or more consultations) - which should change the outcome of risk-pregnancies - the percentages are 77.8% and 12.2% respectively (Tab. III). Pregnancies resulting in babies with birth weight of 2501 g -2750 g exceeded the limit in 38.9% and those with babies of 2751 g-3000 g in 20.7%. If 60 risk points are used as the limit the percentages for more than 3000 g until less than 2501 g would be 8.2%, 6.9%, 33.3% and 66.7%. In the resrospective study (Tab. V) 14.7% of all pregnancies with babies above 3000 g exceeded the 50 risk points limit compared with 57.2 of those with babies below 2501 g. Excluding pregnancies with 20 or more risk points and excellent prental care the percentages are 7.6 and 59.4 respectively. In the retrospective study the influence of the quality of prenatal care by the number of consultations (3-4; 5-7; 8 or more) is clearly demonstrable: Pregnancies with more than 50 risk points resulted in 80.7%, 57.1% and 19.8% depending on the quality of care in babies below 2501 g. Pregnancies with 31-50 risk points did so in 47.2%, 20.4% and 11.8%. In 334 women the score could be applied twice, in the 6th month and at delivery. Comparing both scores it was found that only 1.8% of these women exceeded the 50 risk points limit by events occurring after the 6th month scoring (Tab. IV). The score, simple enough to be applied by nurses and midwives, seems to be able to select 77.8% of pregnancies resulting in babies below 2501 g already during the 6th month of pregnancy, i.e. early enough for preventive measures to be taken that decrease the frequency of underweight births by three quarters.

Birth Weight↗

[Results of dermatoglyphic studies in the Roussy-Lévy syndrome].

Dermatoglyphics performed on the three persons with fully developed RLS as well as on those with partial symptomatology revealed a striking agreement as to their pappilary systems and the characteristic deviation from the norm: irregularities on the pattern of the ridges of the finger and toe prints and on the soles and palms, a much reduced "total ridge count" (TRC), predominant bow patterns on the toe prints, grid-and reticularpatterned white lines on the soles and palms, loop proliferation on the soles and special shapes of the transverse palmar crease.

Child↗

[Heredo familial areflectoric dystasie. Roussy-Lévy-Syndrome (author's transl)].

The Roussy-Lévy-Syndrome in a 12 years old girl is described and its relation to other heredofamilial ataxias is discussed. The kindred of our patient was studied as well. Information about 21 family members could be collected; 11 of them also suffered from RLS. Additionally for the first time in literature, dermatoglyphic patterns in these patients have been investigated.

Child↗

A neurolinguistic longitudinal study of a pure motor aphasia.

We have made a detailed neurolinguistic study of a patient with motor aphasia. The method used for his reeducation and the variants found in his language from a linguistic point of view through the course of several months are described. During this study we have found similarities with cases studied by Marcie reached by him in the errors common in patients with motor aphasia. But, contrary to Marcies, findings, we have found phonemes and allophones outside of the phonological and/or dilectal system of the language in this area. These phonemes and allophones are described together with the environment in which they appear.

Adult↗

[Infectious skin disease in the newborn (author's transl)].

The most important infectious skin diseases of the newbornperiod are discussed in a short survey. Those skin alterations which can already be observed immediately after birth are especially emphasized. The search for skin infections has to be a routine measure in the care of the newborn, because even the smallest pyoderms can lead to septic complications, and non-infected newborn must be protected through the quarantining and treatment of those newborns with the infection. Frequent occurrence of pyoderms should be taken as a reason for examining the hygienic measures in the delivery room, nursery and maternity ward.

Humans↗

[Preliminary investigations of the serum alpha-1-fetoprotein level in mature and premature newborn infants (author's transl)].

Semiquantitative determination of the serum AFP concentration was carried out in 170 newborn infants (mature and premature) by means of crossover electrophoresis on admission to hospital and at 1 to 2 weekly intervals thereafter. The infants were divided into 3 groups according to their birth weight and also grouped according to gestational age into 3 further groups. The serum AFP level was correlated with the age in weeks of the infants for each group separately. Mature newborn infants with a birth weight of over 2500 g show a rapid fall in serum AFP titre; AFP is no longer detectable after the 9th week of life. In premature infants with a birth weight of 1500 to 2500 g, the fall in AFP titre is delayed and reaches zero between the 7th and 13th week of age. There is a markedly slower decrease in serum AFP concentration in the group of immature infants with a birth weight of under 1500 g; the limit of detectability lies between the 13th and the 17th week of age. An almost identical pattern is revealed when the infants are grouped according to gestational age. The possibility of diagnosing the small for date babies and severe liver disease by means of the serum AFP titre is discussed.

Age Factors↗

[Results of a follow up study of small for date babies. I. Physical development (author's transl)].

74 small for date babies were investigated at the age of 10 years. The first part of the paper deals with the children's physical development and state of health. An attempt to correlate the degree of intrauterine malnutrition and postnatal development was made taking into account possible etiological factors, genetic, pre- and postnatal influences. Four children who had been exposed to several harmful intrauterine factors showed general developmental retardation. All the other childrens demonstrated normal physical development including the group who had shown signs of prolonged intrauterine malnutrition.

Adult↗

[Results of a follow up study of small for date babies. II. Mental development (author's transl)].

The second part of the follow-up investigation of 74 small for date babies presents the results of neurological investigation and psychological testing. A correlation was found between the period of the intrauterine noxa and the results. A third of the children in group I (where the intrauterine influences were more severe and more prolonged) had an IQ below average. Minor cerebral damage, poor school performance and mental disturbance were significantly more common than in group II. The EEG-investigation did not contribute additional information. In both groups social factors had an important influence.

Body Height↗