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Biomedical subjects

A Piskarskas

Publications and source records attributed to A Piskarskas.

12 recordsLinked to original sources

Near- and far-field evolution of laser pulse filaments in Kerr media.

Measurements of the spatio-temporal and far-field profiles of ultrashort laser pulses experiencing conical emission, continuum generation, and beam filamentation in a Kerr medium outline the spontaneous formation of wave packets with X -like features, thus supporting recent numerical results [M. Kołesik, E. Wright, and J. Moloney, Phys. Rev. Lett. 92, 253901 (2004)]. Numerical simulations show good agreement with experimental data.

Computer Simulation↗

Multimillijoule chirped parametric amplification of few-cycle pulses.

The concept of optical parametric chirped-pulse amplification is applied to attain pulses with energies up to 8 mJ and a bandwidth of more than 100 THz. Stretched broadband seed pulses from a Ti:sapphire oscillator are amplified in a multistage noncollinear type I phase-matched beta-barium borate parametric amplifier by use of an independent picosecond laser with lock-to-clock repetition rate synchronization. Partial compression of amplified pulses is demonstrated down to a 10-fs duration with a down-chirped pulse stretcher and a nearly lossless compressor comprising bulk material and positive-dispersion chirped mirrors.

Journal Article↗

Nonlinear space-time dynamics of ultrashort wave packets in water.

We have monitored the space-time transformation of a 150-fs pulse undergoing self-focusing and filamentation in water, by means of the nonlinear gating technique. We have observed that pulse splitting and subsequent recombination apply to axial temporal intensity only, whereas the space-integrated pulse profile preserves its original shape.

Journal Article↗

Spatiotemporal three-dimensional mapping of nonlinear X waves.

The spatiotemporal intensity profile of a 100-fs wave packet at the output of a X2 crystal, tuned for mismatched second-harmonic generation, is probed via sum-frequency generation with a compressed, 20-fs pulse, revealing the appearance of an X-type wave shape.

Journal Article↗

Spatial versus temporal deterministic wave breakup of nonlinearly coupled light waves.

We investigate experimentally the competition between spatial and temporal breakup due to modulational instability in chi((2)) nonlinear mixing. The modulation of the wave packets caused by the energy exchange between fundamental and second-harmonic components is found to be the prevailing trigger mechanism which, according to the relative weight of diffraction and dispersion, leads to the appearance of a multisoliton pattern in the low-dimensional spatial or temporal domain.

Journal Article↗

Spontaneously generated X-shaped light bullets.

We observe the formation of an intense optical wave packet fully localized in all dimensions, i.e., both longitudinally (in time) and in the transverse plane, with an extension of a few tens of fsec and microns, respectively. Our measurements show that the self-trapped wave is an X-shaped light bullet spontaneously generated from a standard laser wave packet via the nonlinear material response (i.e., second-harmonic generation), which extend the soliton concept to a new realm, where the main hump coexists with conical tails which reflect the symmetry of linear dispersion relationship.

Journal Article↗

Nonlinear X waves in second-harmonic generation: experimental results.

X waves, spatiotemporal generalization of the monochromatic Bessel- (or Durnin-) type beams, are known in linear acoustic, microwave and optics for their unique property of defeating both spatial and temporal spreadings. Recently, we brought to the attention that X-type waves are also the key to understand the spatiotemporal dynamics observed in the nonlinear (high intensity) regime. Indeed, X waves represent the normal-propagation mode for a wide class of parametric interactions described by hyperbolic nonlinear models featuring spatial self-focusing and temporal self-broadening. Here, we provide a complete and detailed description of the experiment in which the spontaneous appearance of X waves has been observed. The experiment concerns frequency doubling of a 170-fs, 50-microm standard laser wave packet in a 22-mm lithium triborate crystal, tuned for second-harmonic generation with positive phase mismatch, positive group-velocity dispersion, and large group-velocity mismatch. Conventional beam-profile and autocorrelation measurements at the crystal output face show evidence of spatiotemporal self-trapping. The characterization of the free-space propagation reveals sub-Gaussian diffraction and pulse broadening, consistent with the presence of angular dispersion. Space-resolved autocorrelations indicate the generation of an X-type profile.

Journal Article↗

Nonlinear electromagnetic X waves.

Nonlinear optical media that are normally dispersive support a new type of localized (nondiffractive and nondispersive) wave packets that are X shaped in space and time and have slower than exponential decay. High-intensity X waves, unlike linear ones, can be formed spontaneously through a trigger mechanism of conical emission, thus playing an important role in experiments.

Journal Article↗

Observation of quadratic optical vortex solitons

We report on the generation of stable dark-vortex solitons in large-phase-mismatched second-harmonic generation of self-defocusing type, sustained by a combined effect of transverse walk-off and finite beam size.

Journal Article↗

Fluence-rate-dependent photosensitized oxidation of NADH.

The photosensitizing activity of dimethoxyhaematoporphyrin, excited by a laser pulse at 532 nm (YAG-Nd3+), was investigated using reduced nicotinamide adenine dinucleotide (NADH) as a substrate. The photo-oxidative modification of NADH was monitored by measuring the absorbance at 340 nm. The use of nanosecond pulses (15 and 0.5 ns) resulted in photosensitized NADH oxidation which depended on the fluence but not on the fluence rate up to a peak fluence rate of 10(7) W cm-2. At higher fluence rates a decrease in NADH photo-oxidation was observed, as well as on irradiation with picosecond pulses (35 ps). Stern-Volmer assay of the quenching by sodium azide revealed a decrease in quenching efficiency with increasing peak fluence rate. Oxidation of NADH was not suppressed by the addition of 20 mM sodium azide at peak fluence rates above 6 x 10(9) W cm-2. This observation, as well as the significant bleaching of dye absorption, indicates excitation of the photosensitizer into higher lying excited singlet states and the involvement of processes other than photodynamic action.

Hematoporphyrin Derivative↗