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Biomedical subjects

A Pinckers

Publications and source records attributed to A Pinckers.

At least 73 records · Page 4Linked to original sources

Lanthony's new color test. IV. Neutral zone and neutral grays.

The classification of neutral grays is helpful for the differential diagnosis of color vision defects, especially when anomaloscopic examination is not possible. In congenital color vision defects the PR, RP region of the spectrum appears 'dark' to protan-defective subjects and 'light' to deutan-defective subjects. Acquired color vision defects have a common base type, the type III blue-yellow defect. The defect develops depending on the site of the primary lesion and also on the fixation mode. Classification of neutral grays may help in differentiating optic nerve diseases from retinal diseases; when visual functions become mediated by rods, sensitivity shifts and the BV, B region of the spectrum will appear relatively 'light' to the patient.

Color Perception Tests↗

Tokyo Medical College Test in acquired dyschromatopsia.

In order to find a successor for the Hardy, Rand and Rittler (AOH-R-R) test the author made a comparison between the AOH-R-R and the Tokyo Medical College (TMC) tests in acquired dyschromatopsia. The diagnosis of the TMC type of a red-green defect is often in contradiction with the results of other color vision tests. In grading the severity of a red-green defect the TMC classification is shifted with regard to the AOH-R-R classification. A corrected grading in better agreement with the AOH-R-R classification is proposed. The TMC blue-yellow screening plates are more sensitive than the AOH-R-R blue-yellow screening plates. A TMC (supermild) blue-yellow defect in general corresponds to blue-yellow defects detected by FM 100 Hue and its derivatives. In the study of acquired dyschromatopsia, it is necessary to use a test battery. In our opinion the TMC can be used in such a test battery although it is not a real successor to the AOH-R-R. If ever the AOH-R-R is reprinted, the blue-yellow plates should be extended to a 'supermild' degree as are the TMC blue-yellow plates.

Adult↗

Color vision and age.

The results of pseudoisochromatic tests (TMC Ishihara, AOH-R-R) are relatively independent of age. In the Panel D-15, the NCT box 6/4 and the desaturated panel, ageing goes hand in hand with blue-yellow confusions. Fault-positive red-green confusions result from D8/2 examination. For the FM 100 Hue test and the Anomaloscope Nagel, the data found in the literature are confirmed. In nuclear cataract there is no increased shift of the Rayleigh equation towards the green, but towards the red.

Adolescent↗

Lanthony's new color test--part III. The neutral zone.

With the New Color Test (NCT) the neutral zone was studied in hereditary and acquired dyschromatopsias. Acquired type III blue-yellow defects with neutral zone occurred in heredo-atrophies of the optic nerve, in edematous maculopathies, in choroidal atrophy, in myopia, in glaucoma and in retinitis pigmentosa. With exclusion of the autosomal dominant inherited cases, the type III neutral zone in retinitis pigmentosa becomes complicated by a type I neutral zone when the visual acuity dropped to 0.2.

Choroid↗

Clinical electro-oculography.

In clinical routine EOG we are dealing with a base line or lightinsensitive potential and a lightsensitive potential, the latter consisting of at least two different oscillations, a fast negative and a slow positive one. Any judgement of EOG without referring to the absolute level of the baseline is an incomplete one. It is no longer justified to refer to the Arden ratio as a unique parameter for EOG normalty or abnormalty. Our knowledge about the generating mechanisms of the different EOG components is insufficient. Clinical EOG examination is one way to better understanding. Statistical evaluation is not easy because of the considerable inter- and intraindividual variations. The study of uniocular diseases or affections may solve some of our problems.

Electrooculography↗

Lanthony's new color test. Part I.

In general the statements in the manual of the New Color Test are confirmed, but there is no exact correlationship between the AOH-R-R classification and the NCT classification. There is a gradual increase in sensitivity from the AOH-R-R, via the panel D-15 and the NCT 6/2 to the desaturated panel 8/2. Thus, if the panel 8/2 result is normal the NCT 6/2 yields no further information.

Adolescent↗

Lanthony's new color test. II. Clinical evaluation.

The desaturated 15 Hue test is estimated to give about 7% false-positive single protanopic confusions. Confusions between tetartanopic and protanopic directions are not infrequent. The New Color Test findings, in general, reflect the AOH-R-R pathology but, among other things, because of the difference in their size, the classifications of both tests should not be compared. The New Color Test proves to be valuable, and can be easily employed in a routine clinical procedure. An examination scheme is proposed.

Color Perception Tests↗

[Dominant cystoid macular dystrophy (author's transl)].

Dominant cystoid macular dystrophy (D.C.M.D.) is characterized by a macular dystrophy but at the same time by a pigmentary dystrophy of the retinal periphery. Ultimately D.C.M.D. resembles an atypical pigmentary dystrophy, in some cases that of a pericentral retinitis pigmentosa. In an early stage the results of the EOG and darkadaptation curve reflect the process at the level of the peripheral retina, while only in a late stage we may expect some diffuse ERG pathology. D.C.M.D. might be classified as a tapetoretinal dystrophy and in particular as a form of retinitis pigmentosa with an atypical visual disturbance and an atypical fundus appearance (Leber, 1871). In doing so attention is paid to the fact that D.C.M.D. is more than a macular dystrophy. The denomination of the disease as D.C.M.D. reflects the most important features at a relatively young age.

Diagnosis, Differential↗

Peripheral cone disease.

Peripheral cone disease is characterized by an absent cone function as measured by the ERG but a normal or slightly affected colour vision. The authors examined 20 cases. The most striking fact was the high incidence of myopia and the presence of nystagmus; on the basis of this finding the authors suggest that at least some cases of peripheral cone disease are due to myopic choroido-retinal degeneration (in French: "choroïdose myopique").

Adaptation, Ocular↗

Retinal functions in dominant cystoid macular dystrophy (DCMD).

Dominant cystoid macular dystrophy (DCMD) occurred in 28 members of 5 unrelated families. The disease is characterized by cystoid macular oedema and leakage from retinal capillaries in the posterior pole. Colour vision examination reveals a type I red-green defect with concomitant blue-yellow defectiveness; the latter may be caused by the leaking capillaries. The ERG is normal. The EOG is subnormal. Darkadaptation curves are often slightly disturbed. There are frequently also aspecific pigmentary alterations in the peripheral fundus.

Color Perception↗