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Biomedical subjects

A Pigoń-Wegiel

Publications and source records attributed to A Pigoń-Wegiel.

11 recordsLinked to original sources

[Sporadic case of leptospirosis].

The flood disaster involves the danger of development of dangerous epidemic and episodic events on leptospirotic endemic area in the nearest spring and summer. The authors present a case of severe hemolytic leptospirosis as a results of gastrointestinal tract infection of 3 strains of leptospira. Polymorphism leptospirotic symptoms were discussed. The authors suggest the concept of the influence of plasma betaphospho-lipoprotein deficiency on cytoplasmatic respiration and substrate phosphorylation of morphologic elements of the blood, vessel endothelium and stroma cells.

Adolescent↗

[Plasma pancreatic glucagon during glucose tolerance test in workers exposed to vibration and noise].

Pancreatic glucagon plasma concentration (IR-G) were measured during oral glucose tolerance test (GTT) in workers exposed to whole body vibration and noise. In workers with abnormal GTT higher IR-G concentrations were found in comparison with the control group. Langerhans islet alfa cells stimulation may be responsible for a higher frequency of elevated glycemia during GTT in workers exposed to whole body vibration and noise.

Adult↗

[Glucose tolerance test and insulinemia in workers occupationally exposed to vibration and noise].

Oral glucose test and serum insulin determination was performed in 192 workers of a large metallurgical factory. The subjects were divided into four groups: 1. exposed to isolated noise, 2. exposed to local vibration, 3. exposed to the whole body vibration, and 4. control group. In the group exposed to the whole body vibration more frequent occurrence of higher glucose and serum insulin concentrations were found when compared with the control group. The observed changes were caused by low and medium frequency of the whole body vibration.

Adult↗

[Low frequency vibration and testosterone levels in blood serum and excretion of 17-ketosteroid in urine in exposed workers].

Serum testosterone concentrations and excretion of 17-Ketosteroid in urine were determined in 32 caterpillar vehicle drivers exposed to low frequency vibration of the whole body and to noise. Testosterone concentrations were assessed by the RIA method in fasting after 3 hrs of work. 17-Ketosteroid excretion was measured in the 8-hr collection of night urine and in urine collected during the day's work. No significant differences were found in exposed workers, either in mean testosterone concentration in fasting and after 3 hrs of work or in 17-Ketosteroid excretion, before and during the work, when compared with the control group.

17-Ketosteroids↗

[Secretion of insulin and peptide C in workers exposed to whole body vibration and noise].

Insulin and C-peptide concentrations were studied in serum (by means of radioimmunoassay) after an oral glucose tolerance test in 62 workers occupationally exposed to whole body vibration and noise, and in 30 non-exposed workers of the control group. In the exposed group more frequent occurrence of higher glucose and insulin concentrations, with normal C-peptide concentrations, were found. The observed non-effective hyperinsulinaemia is likely caused by an impaired insulin degradation in the liver and/or an increased production of proinsulin which is assayed simultaneously by IR-I method.

Adult↗

[Electrocardiographic examination of the heart and the study of catecholamine secretion in workers subjected to mechanical vibration and occupational noise].

Electrocardiographic tests in 281 workers of metallurgical industry, exposed for 3-20 years to mechanical and acoustic vibrations exceeding allowable standards, were carried out. The control group consisted of 120 subjects unexposed to physical or chemical hazards. In 82 subjects exposed to vibration and noise, 43 workers exposed to isolated noise and 30 subjects of the control group, the amount of 3 methoxy--4 hydroxymandelic (3M4HM) acid before and after work was determined. Significantly more frequent repolarization disturbances of neurovegetative nature (V-3), particularly in those simultaneously exposed to general and local vibration, were evidenced. In those exposed exclusively to noise no ECG changes were found. In addition, increased 3M4HM secretion, due to both local and whole--body transmitted vibration, was found. Isolated noise does not induce an increase in 3M4HM secretion.

Adult↗

[Blood coagulation system in workers exposed to noise and vibration].

The authors examined the blood coagulation system in the following 3 groups of workers occupationally exposed to noise and vibration: A--those in whom the examination was conducted 7--16 hrs after finishing the work, B--those in whom the examination was conducted at the 3rd or 4th hour of work, and C--those suffering from angioneurosis of the vibration syndrome of II or III period who have not been exposed to vibration for some recent years. These investigations indicated the lack of blood equilibrium tending to hypercoagulability, shortened duration of plasma recalcination, increased elasticity coefficient of mE thromboelastogram coagulation, increased fibrinogen concentration; these changes were most evident in the group with advanced vibration disease and in those in whom the examination was conducted at their working time. Fibrinolysis duration was significantly prolonged during work, and shortened in those with advanced angioneurosis. In the opinion of the authors, those disturbances in the blood equilibrium system may be accounted for by the conformation changes of proteins.

Adult↗

[Preleukemia].

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Adult↗