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Biomedical subjects

A Pietraszek

Publications and source records attributed to A Pietraszek.

38 records · Page 3Linked to original sources

[Elective (prophylactic) brain irradiation in small cell lung cancer patients treated with chemotherapy combined with surgery].

The incidence of brain metastases in small cell lung cancer patients in the group without prophylactic cranial irradiation (PCI) was compared with the incidence of brain secondaries after PCI. Out of 29 patients without brain irradiation 13 patients experienced brain metastases at 19 months (13/29). On the contrary, no one out of 17 patients who received PCI was found to have brain metastases at 4 years. The justification of prophylactic cranial irradiation is presented and criteria of patients selection are given. Elective brain irradiation is indicated exclusively in patients with "limited disease" achieving complete response.

Brain Neoplasms↗

[Initial concentration of the neoplastic biological markers AFP (alpha fetoprotein), HCG (chorionic gonadotropin), and SP1 (specific pregnancy protein) in separate types and stages of clinically advanced lung cancer].

Determination of neoplastic biological markers has been done in 709 patients including determination of AFP in 142, HCG in 324 and SP1 in 243 cases. Among 142 patients in whom AFP has been determined in 2 cases only (1.4%) the elevated level has been present. Elevated levels of HCG have been found in 19 out 324 cases (5.9%) and SP1 in 29 out 243 cases (11.9%).

Biomarkers, Tumor↗