[Dose-dependence of intestinal iron absorption in sucking pigs].
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Biomedical subjects
Publications and source records attributed to A Pfau.
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A case of generalized neurofibromatosis (von Recklinghausen's disease) associated with hypertension is presented. Adequate repair of the unilateral main artery stenosis did not result in cure of the hypertension because of diffuse neurofibromatous lesions of the smaller renal vessels. Review of the literature reveals that neurofibromatosis of the large and small renal vessels should be suspected in every hypertensive patient with these lesions below the age of eighteen. In view of the fact that vascular neurofibromatosis is a dynamic and spreading disease, surgery of the renal vessels should be reconstructive as much as possible.
6 cases with chronic bacterial prostatitis were reviewed. The effort and patience required to diagnose this condition accurately by means of differential urine and prostatic secretion cultures is extremely worthwhile. Cotrimoxazole, which has been suggested as a most effective antibacterial drug in chronic bacterial prostatitis, cured only 3 out of our 6 patients and then only after continuous treatment for 4 months. 2 of the remaining patients were cured by a 10 to 14 days' course of kanamycin and the third was probably cured by streptomycin. On theoretical grounds neither of these lipid insoluble drugs should be capable of penetrating the prostatic epithelium. The implications of these findings are discussed.
As a result of previous in-vitro studies on the alpha-adrenergic receptor activity of the human prostate and prostatic capsule a trial was made of alpha-adrenergic blockers for the relief of obstructive prostatic symptoms. Considerable benefit was obtained in several groups of patients, as demonstrated either by the relief or prevention of complete retention, or by diminution in residual urine or improvement in urinary flow-rate recordings. A number of illustrative cases are described, and the indications for the use of this treatment are suggested. It is emphasised that this treatment provides symptomatic relief only, and in no sense purports to be a treatment of the enlarged prostate itself.
3 patients with suspected renal segmental ischaemia are presented. In 2 of them segmental renal artery stenosis was demonstrated radiographically and the differential renal function studies predicted the outcome of surgery accurately. In the last patient no segmental renal artery stenosis was demonstrated on angiography, and surgery did not benefit this patient in spite of positive differential renal function studies for "curable" renal segmental ischaemia. Some haemodynamic aspects, as expressed by the differential renal function studies, are discussed.
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